DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6654 and M1BP

DIOPT Version :9

Sequence 1:	NP_650429.1	Gene:	CG6654 / 41831	FlyBaseID:	FBgn0038301	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_649825.1	Gene:	M1BP / 41042	FlyBaseID:	FBgn0037621	Length:	418	Species:	Drosophila melanogaster

Alignment Length:	187	Identity:	66/187 - (35%)
Similarity:	91/187 - (48%)	Gaps:	14/187 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   459 KLRHSETKS------FKCELCPHSFVTKAELTSHARTHTGDKPFECEVCLARFTTSCSLAKHKRK 517
            |:|..:.:.      :.||.|.:....:.....|.|.|.|||.|.||:|.:||.|:..|.:|.||
  Fly   236 KVRSDDARRRGTGGVYICEQCGNHIKGRMAFELHCRRHRGDKQFGCELCQSRFCTTSELKRHMRK 300

  Fly   518 HTGERPYACDLCPMRFTALNVLKNHRRTHTGERPYVCPFCSKTFTQRGDCQMHQRTHQGERIYIC 582
            ||||||:||..|...||.......|.||||.||||||..|.|.||.....:.|...|.|||.|.|
  Fly   301 HTGERPFACKYCGRCFTDYTTRVKHERTHTNERPYVCGTCGKAFTTGYILKNHMLIHSGERAYRC 365

  Fly   583 PVCNEEFKSMPEMRSHLAG--HEQHDKRLVHFTFLSNKENGSGALEEELNEMTESAL 637
            .:|::.|.....:.:|...  |::|.::......|..::      :.||.|..|.:|
  Fly   366 ELCDKSFMLPTHLSTHFRSGVHKRHLEKAEMKQVLEQEQ------KRELKEEEEDSL 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6654	NP_650429.1	zf-AD	6..79	CDD:285071
		C2H2 Zn finger	331..354	CDD:275368
		COG5048	<357..570	CDD:227381	48/116 (41%)
		C2H2 Zn finger	360..380	CDD:275368
		C2H2 Zn finger	385..406	CDD:275370
		C2H2 Zn finger	414..434	CDD:275368
		zf-H2C2_2	427..451	CDD:290200
		C2H2 Zn finger	442..490	CDD:275368	7/36 (19%)
		C2H2 Zn finger	470..487	CDD:275368	3/16 (19%)
		zf-H2C2_2	482..507	CDD:290200	12/24 (50%)
		C2H2 Zn finger	498..518	CDD:275368	9/19 (47%)
		zf-H2C2_2	510..534	CDD:290200	13/23 (57%)
		C2H2 Zn finger	526..546	CDD:275368	6/19 (32%)
		zf-H2C2_2	539..563	CDD:290200	14/23 (61%)
		C2H2 Zn finger	554..574	CDD:275368	6/19 (32%)
		C2H2 Zn finger	582..602	CDD:275368	4/21 (19%)
M1BP	NP_649825.1	zf-AD	13..84	CDD:214871
		C2H2 Zn finger	253..273	CDD:275368	5/19 (26%)
		COG5048	276..>331	CDD:227381	28/54 (52%)
		C2H2 Zn finger	281..301	CDD:275368	9/19 (47%)
		zf-H2C2_2	293..317	CDD:290200	13/23 (57%)
		C2H2 Zn finger	309..329	CDD:275368	6/19 (32%)
		zf-H2C2_2	324..346	CDD:290200	14/21 (67%)
		C2H2 Zn finger	337..357	CDD:275368	6/19 (32%)
		zf-H2C2_2	350..372	CDD:290200	8/21 (38%)
		C2H2 Zn finger	365..383	CDD:275368	4/17 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I1804
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960