DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6654 and ZBTB34

DIOPT Version :9

Sequence 1:NP_650429.1 Gene:CG6654 / 41831 FlyBaseID:FBgn0038301 Length:639 Species:Drosophila melanogaster
Sequence 2:NP_001382127.1 Gene:ZBTB34 / 403341 HGNCID:31446 Length:514 Species:Homo sapiens


Alignment Length:533 Identity:110/533 - (20%)
Similarity:170/533 - (31%) Gaps:183/533 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   118 SVQTDAVT--TTDAEQNTSLIKSTISVDLDYEGEGEVFDYELPDEPVEKTTSLILQVQGNLKDEK 180
            ||:.|:.:  ..|..:.:|.:.|.:: :|..:|               |...:|:.:||......
Human    12 SVEMDSSSFIQFDVPEYSSTVLSQLN-ELRLQG---------------KLCDIIVHIQGQPFRAH 60

  Fly   181 EVVFTQTNVIYEGDDHELEQQIRECNLAIFEGVDNEAEII--------TVTAPQVTTRKSAAKLL 237
            :.|...::..:.  ||.....:...::::.:..:...:::        ::....|.:..:||..|
Human    61 KAVLAASSPYFR--DHSALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQLKDVVSFLTAASFL 123

  Fly   238 TQQ----------ENDKHQTPVGSKEEARELEKEQVPQSAKRTSRRRGVVKQDVPATPPSDAEPS 292
            ..|          |:...:..||..:.. .:..|:.|:|      |.||......|.|   .|.|
Human   124 QMQCVIDKCTQILESIHSKISVGDVDSV-TVGAEENPES------RNGVKDSSFFANP---VEIS 178

  Fly   293 PKQHRLGTQRKLSAPRAGTVNGPSTTSGAATTPELKY--HCDRCNAGFAVEKSLMIH--RRQKGC 353
            |.....|.|     |.|.:.....||...|....|:.  |.||.::|...|..:.|.  ..|...
Human   179 PPYCSQGRQ-----PTASSDLRMETTPSKALRSRLQEEGHSDRGSSGSVSEYEIQIEGDHEQGDL 238

  Fly   354 INRNYKCNECEKVFVSPDH----------------------------------LAEH-----QAS 379
            :.|..:..|.:......|.                                  :.:|     ||:
Human   239 LVRESQITEVKVKMEKSDRPSCSDSSSLGDDGYHTEMVDGEQVVAVNVGSYGSVLQHAYSYSQAA 303

  Fly   380 HGAHNCPEC------------------GIRCDSKEALSKH-------MVQG-------------- 405
            ....|..|.                  |.|...|.|||.|       :|||              
Human   304 SQPTNVSEAFGSLSNSSPSRSMLSCFRGGRARQKRALSVHLHSDLQGLVQGSDSEAMMNNPGYES 368

  Fly   406 --HKRNLRNQ---------CNICQKVFTMLSTLRDHMRIHTGEKPFVCNICGKSFTQNANLRQHK 459
              .:|:.|..         |..|.|.|....:|..|||:|.|..||||..|||.:|:        
Human   369 SPRERSARGHWYPYNERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTR-------- 425

  Fly   460 LRHSETKSFKCELCPHSFVTKAELTSHARTHTGDKPFECEVCLARFTTSCSLAKHKRK-HTG--- 520
                                |.:|..|.|.||.||||.||:|...|....:|.:|.|| |.|   
Human   426 --------------------KDQLEYHIRGHTDDKPFRCEICGKCFPFQGTLNQHLRKNHPGVAE 470

  Fly   521 -----ERPYACDL 528
                 |.|...|:
Human   471 VRSRIESPERTDV 483

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6654NP_650429.1 zf-AD 6..79 CDD:285071
C2H2 Zn finger 331..354 CDD:275368 6/24 (25%)
COG5048 <357..570 CDD:227381 60/270 (22%)
C2H2 Zn finger 360..380 CDD:275368 5/58 (9%)
C2H2 Zn finger 385..406 CDD:275370 11/61 (18%)
C2H2 Zn finger 414..434 CDD:275368 8/19 (42%)
zf-H2C2_2 427..451 CDD:290200 13/23 (57%)
C2H2 Zn finger 442..490 CDD:275368 9/47 (19%)
C2H2 Zn finger 470..487 CDD:275368 2/16 (13%)
zf-H2C2_2 482..507 CDD:290200 13/24 (54%)
C2H2 Zn finger 498..518 CDD:275368 8/20 (40%)
zf-H2C2_2 510..534 CDD:290200 9/28 (32%)
C2H2 Zn finger 526..546 CDD:275368 1/3 (33%)
zf-H2C2_2 539..563 CDD:290200
C2H2 Zn finger 554..574 CDD:275368
C2H2 Zn finger 582..602 CDD:275368
ZBTB34NP_001382127.1 BTB_POZ_ZBTB34 21..140 CDD:349529 18/136 (13%)
C2H2 Zn finger 388..408 CDD:275368 8/19 (42%)
zf-H2C2_2 400..425 CDD:404364 13/24 (54%)
C2H2 Zn finger 416..436 CDD:275368 9/47 (19%)
zf-H2C2_2 429..451 CDD:404364 12/21 (57%)
zf-C2H2 442..463 CDD:395048 7/20 (35%)
C2H2 Zn finger 444..462 CDD:275368 6/17 (35%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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