DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6654 and Zbtb42

DIOPT Version :9

Sequence 1:NP_650429.1 Gene:CG6654 / 41831 FlyBaseID:FBgn0038301 Length:639 Species:Drosophila melanogaster
Sequence 2:NP_001093930.1 Gene:Zbtb42 / 382639 MGIID:3644133 Length:420 Species:Mus musculus


Alignment Length:495 Identity:97/495 - (19%)
Similarity:162/495 - (32%) Gaps:157/495 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   156 ELPDEPVEKTTSLILQVQGNLKDEKEVVFTQTNVIYEGDDHELEQQ--IRECNLAIF-------- 210
            |.|:..|        ::.|.|:.::|:.|.....:..||......:  :..|::...        
Mouse     2 EFPEHGV--------RLLGRLRQQRELGFLCDCTVLVGDARFPAHRAVLAACSVYFHLFYRDQPA 58

  Fly   211 ---EGVDNEAEIITVTAPQVTTRKSAAKLLT---QQENDKHQTPVGSKEE----ARELEKEQVPQ 265
               :.|....:|:||.|        .::||.   :...|.|..||   |:    |..|....:.:
Mouse    59 SSRDTVRLNGDIVTVPA--------FSRLLDFMYEGRLDLHNLPV---EDVLAAASYLHMYDIVK 112

  Fly   266 SAKRTSRRRG------VVKQDVPATPP----------SDAEPSPKQHRLGTQRKLSAPRAGTVNG 314
            ..|...|::.      .:..::|..||          ..|.|..|...||.:.....|..|    
Mouse   113 VCKGRLRKKDPDLETRTLGTELPGQPPHPLPSWSPAFCQAAPKAKHPSLGVKATHPLPTFG---- 173

  Fly   315 PSTTSGAATTPELKYHCDRCNAGFAVEKSLMIHRRQKGCINRNYKCNECEKVFVSPDHLAEHQAS 379
                                      ..|..:..:..|.::.:.|        .||.....|   
Mouse   174 --------------------------PPSWQVAEQSSGALDLSLK--------PSPRPEQVH--- 201

  Fly   380 HGAHNCPECGIR---CDSKEALSKHMVQGHKRNLRNQCN------------ICQKVFTMLSTLRD 429
                  |.|.::   |.|.:.:::.:|:..:.:...|.:            :|......|:...:
Mouse   202 ------PPCRLQTSLCSSVQQVAQPLVKAEQDSFSEQDSSSPQSADRSPPPVCASAAQGLAVDLE 260

  Fly   430 HMRIH-TGEKPF--------------------VCNICGKSFTQNANLRQHKLRH-SETKSFKCEL 472
            .:.|. ||.:..                    :|.:|.|.|.....|:.|...| .|..|.:..|
Mouse   261 PLHIEGTGSQQLGLPAEPVLDSEELGPSRHLCICPLCCKLFPSTHALQLHLSAHFRERDSVRARL 325

  Fly   473 CPHSFVTKAELTSHARTHTGDKPFECEVCLARFTTSCSLAKHKRKHTGERPYACDLCPMRFTALN 537
            .|.                |..| .|.:|...|:.:.:|.:|:|.|:||:||.|..|...|...:
Mouse   326 SPE----------------GSVP-TCPLCSKTFSCTYTLKRHERTHSGEKPYTCVQCGKSFQYSH 373

  Fly   538 VLKNHRRTHTGERPYVCPFCSKTFTQRGDCQMHQRT-HQG 576
            .|..|...||.|:|:.|.:|.:.|||.||...|.|. |.|
Mouse   374 NLSRHAVVHTREKPHACRWCERRFTQSGDLYRHVRKFHYG 413

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6654NP_650429.1 zf-AD 6..79 CDD:285071
C2H2 Zn finger 331..354 CDD:275368 2/22 (9%)
COG5048 <357..570 CDD:227381 55/249 (22%)
C2H2 Zn finger 360..380 CDD:275368 3/19 (16%)
C2H2 Zn finger 385..406 CDD:275370 5/23 (22%)
C2H2 Zn finger 414..434 CDD:275368 2/31 (6%)
zf-H2C2_2 427..451 CDD:290200 7/44 (16%)
C2H2 Zn finger 442..490 CDD:275368 11/48 (23%)
C2H2 Zn finger 470..487 CDD:275368 2/16 (13%)
zf-H2C2_2 482..507 CDD:290200 5/24 (21%)
C2H2 Zn finger 498..518 CDD:275368 6/19 (32%)
zf-H2C2_2 510..534 CDD:290200 10/23 (43%)
C2H2 Zn finger 526..546 CDD:275368 5/19 (26%)
zf-H2C2_2 539..563 CDD:290200 9/23 (39%)
C2H2 Zn finger 554..574 CDD:275368 9/20 (45%)
C2H2 Zn finger 582..602 CDD:275368
Zbtb42NP_001093930.1 BTB 14..114 CDD:279045 20/110 (18%)
BTB 25..121 CDD:197585 19/106 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 127..204 17/123 (14%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 222..247 2/24 (8%)
C2H2 Zn finger 294..314 CDD:275368 6/19 (32%)
COG5048 334..>388 CDD:227381 19/53 (36%)
C2H2 Zn finger 334..354 CDD:275368 6/19 (32%)
zf-H2C2_2 347..369 CDD:290200 10/21 (48%)
C2H2 Zn finger 362..382 CDD:275368 5/19 (26%)
C2H2 Zn finger 390..408 CDD:275368 8/17 (47%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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