DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6654 and Kr

DIOPT Version :9

Sequence 1:	NP_650429.1	Gene:	CG6654 / 41831	FlyBaseID:	FBgn0038301	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_001261181.1	Gene:	Kr / 38012	FlyBaseID:	FBgn0001325	Length:	502	Species:	Drosophila melanogaster

Alignment Length:	312	Identity:	83/312 - (26%)
Similarity:	123/312 - (39%)	Gaps:	67/312 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   232 SAAKLLTQQENDKHQTPVGSKEEARELEKEQVPQSAKRTSRRRGVVKQDVPATPPSDAEPSPKQH 296
            :|.:.|..|....|..|..             |.|...|....|....:.|.:.|...||:.|..
  Fly   109 AAQQSLPPQGTHLHSPPAS-------------PHSPLSTPLGSGKHPLNSPNSTPQHHEPAKKAR 160

  Fly   297 RLGTQRKLSAPRAGTVNGPSTTSGAATTPELKYHCDRCNAGFAVEKSLMIHRRQKGCINRNYKCN 361
            :|..:::.....:.:||....|||...:|.        ::|
  Fly   161 KLSVKKEFQTEISMSVNDMYHTSGGPISPP--------SSG------------------------ 193

  Fly   362 ECEKVFVSPDHLAEHQASHGAHNCPECGIRCDSKEALSKHMVQGHKRNLRNQCNICQKVFTMLST 426
                  .||:  :.|..:.|...|  .|:..|.            .|:....|.||.:.|.....
  Fly   194 ------SSPN--STHDGAGGNAGC--VGVSKDP------------SRDKSFTCKICSRSFGYKHV 236

  Fly   427 LRDHMRIHTGEKPFVCNICGKSFTQNANLRQHKLRHSETKSFKCELCPHSFVTKAELTSHARTHT 491
            |::|.|.|||||||.|..|.|.||::.:|:.|...|:..|.:.|..|...||..|.|..|.|.||
  Fly   237 LQNHERTHTGEKPFECPECHKRFTRDHHLKTHMRLHTGEKPYHCSHCDRQFVQVANLRRHLRVHT 301

  Fly   492 GDKPFECEVCLARFTTSCSLAKHKRKHTGERPYACDLCPMRFTALNVLKNHR 543
            |::|:.||:|..:|:.|..|..|...|.||:|:.|:.|.|:|...:.|.||:
  Fly   302 GERPYTCEICDGKFSDSNQLKSHMLVHNGEKPFECERCHMKFRRRHHLMNHK 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6654	NP_650429.1	zf-AD	6..79	CDD:285071
		C2H2 Zn finger	331..354	CDD:275368	1/22 (5%)
		COG5048	<357..570	CDD:227381	61/187 (33%)
		C2H2 Zn finger	360..380	CDD:275368	3/19 (16%)
		C2H2 Zn finger	385..406	CDD:275370	3/20 (15%)
		C2H2 Zn finger	414..434	CDD:275368	7/19 (37%)
		zf-H2C2_2	427..451	CDD:290200	14/23 (61%)
		C2H2 Zn finger	442..490	CDD:275368	17/47 (36%)
		C2H2 Zn finger	470..487	CDD:275368	6/16 (38%)
		zf-H2C2_2	482..507	CDD:290200	11/24 (46%)
		C2H2 Zn finger	498..518	CDD:275368	7/19 (37%)
		zf-H2C2_2	510..534	CDD:290200	9/23 (39%)
		C2H2 Zn finger	526..546	CDD:275368	7/18 (39%)
		zf-H2C2_2	539..563	CDD:290200	3/5 (60%)
		C2H2 Zn finger	554..574	CDD:275368
		C2H2 Zn finger	582..602	CDD:275368
Kr	NP_001261181.1	C2H2 Zn finger	224..244	CDD:275368	7/19 (37%)
		zf-H2C2_2	237..261	CDD:290200	14/23 (61%)
		C2H2 Zn finger	252..272	CDD:275368	7/19 (37%)
		zf-H2C2_2	264..289	CDD:290200	7/24 (29%)
		C2H2 Zn finger	280..300	CDD:275368	8/19 (42%)
		zf-H2C2_2	292..316	CDD:290200	10/23 (43%)
		C2H2 Zn finger	308..328	CDD:275368	7/19 (37%)
		zf-H2C2_2	321..345	CDD:290200	10/23 (43%)
		C2H2 Zn finger	336..352	CDD:275368	5/15 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010