DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6654 and Zbtb43

DIOPT Version :9

Sequence 1:NP_650429.1 Gene:CG6654 / 41831 FlyBaseID:FBgn0038301 Length:639 Species:Drosophila melanogaster
Sequence 2:NP_001012094.1 Gene:Zbtb43 / 311872 RGDID:1310287 Length:503 Species:Rattus norvegicus


Alignment Length:486 Identity:96/486 - (19%)
Similarity:154/486 - (31%) Gaps:171/486 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   153 FDYELPDEPVEKTTSLILQ-----------------VQGNLKDEKEVVFTQTNVIYEGDDHELEQ 200
            |..|.||     .:|.|||                 |||::....:.|...::..:  .|..|.:
  Rat    44 FQVEFPD-----FSSTILQKLNQQRQQGQLCDVSIVVQGHIFQAHKAVLAASSPYF--CDQVLLK 101

  Fly   201 QIRE------CNLAIFEGV--DNEAEIITVTAPQVTTRKSAAK--------------------LL 237
            ..|.      .|..:||.:  .:....:.:.||::.:..:||.                    :|
  Rat   102 NSRRIVLPDVMNPRVFENILLFSYTGRLVMPAPEIVSYLTAASFLQMWHVVDKCTEVLEGNPTVL 166

  Fly   238 TQQEN--DKHQTPVGSK---------------------EEARELEKEQVPQSAKRTSRRRGVVKQ 279
            .|:.|  ..||:|..|.                     :|.|:.|.|:  :|.|.....:....:
  Rat   167 CQKLNHGSDHQSPSSSNYNGLAESFELGSGGHTDFPKAQELRDGENEE--ESTKDELSSQVTEHE 229

  Fly   280 DVPATPPSDAEPSPKQHRLGTQRKLSAPRAGTVNGPSTTSGAATTPELKYHCDRCNAGFAVEKSL 344
            .:|      :..|.:..||.|:........||  ..||          ::|..|   ....:.|:
  Rat   230 YLP------SNSSTEHDRLSTEMASQDGEEGT--NDST----------EFHYTR---PLYSKPSI 273

  Fly   345 MIHRRQKGCINRNYKCNECEKVFVSPDHLA-------------EHQASHGA------HNCPECG- 389
            |.|||.               :.|.|:.|.             |||.|...      |:....| 
  Rat   274 MPHRRW---------------IHVKPERLEQPWDGMDVHAAYDEHQVSESVNTMQTDHSAQPSGA 323

  Fly   390 ------------IRCD----------------------SKEALSKHMVQGHKRNLRNQCNICQKV 420
                        :..|                      |.|.|...:: |||:.........:.:
  Rat   324 EEEFQIVEKKVEVEFDEHAEGSNYDEQVDFYGSSMEEFSGEKLGGGLI-GHKQETALAAGYSENI 387

  Fly   421 FTMLSTLRD--HMRIHTGEKPFVCNICGKSFTQNANLRQHKLRHSETKSFKCELCPHSFVTKAEL 483
            ..::....:  |:.....:|.:.|. ||||||..:...:|...|...:.:.|.:|...|..|..|
  Rat   388 EMVMGIKEEASHLGFSATDKLYPCQ-CGKSFTHKSQRDRHMSMHLGLRPYGCSVCGKKFKMKHHL 451

  Fly   484 TSHARTHTGDKPFECEVCLARFTTSCSLAKH 514
            ..|.:.|||.||:||.:|..||....|..:|
  Rat   452 VGHMKIHTGIKPYECNICAKRFMWRDSFHRH 482

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6654NP_650429.1 zf-AD 6..79 CDD:285071
C2H2 Zn finger 331..354 CDD:275368 6/22 (27%)
COG5048 <357..570 CDD:227381 45/214 (21%)
C2H2 Zn finger 360..380 CDD:275368 6/32 (19%)
C2H2 Zn finger 385..406 CDD:275370 5/55 (9%)
C2H2 Zn finger 414..434 CDD:275368 1/21 (5%)
zf-H2C2_2 427..451 CDD:290200 8/25 (32%)
C2H2 Zn finger 442..490 CDD:275368 15/47 (32%)
C2H2 Zn finger 470..487 CDD:275368 5/16 (31%)
zf-H2C2_2 482..507 CDD:290200 12/24 (50%)
C2H2 Zn finger 498..518 CDD:275368 6/17 (35%)
zf-H2C2_2 510..534 CDD:290200 2/5 (40%)
C2H2 Zn finger 526..546 CDD:275368
zf-H2C2_2 539..563 CDD:290200
C2H2 Zn finger 554..574 CDD:275368
C2H2 Zn finger 582..602 CDD:275368
Zbtb43NP_001012094.1 BTB_POZ_ZBTB43 44..164 CDD:349536 22/126 (17%)
C2H2 Zn finger 412..430 CDD:275368 7/18 (39%)
C2H2 Zn finger 438..458 CDD:275368 6/19 (32%)
zf-H2C2_2 450..473 CDD:404364 10/22 (45%)
C2H2 Zn finger 466..483 CDD:275368 6/17 (35%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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