DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6654 and Gzf1

DIOPT Version :9

Sequence 1:NP_650429.1 Gene:CG6654 / 41831 FlyBaseID:FBgn0038301 Length:639 Species:Drosophila melanogaster
Sequence 2:NP_001101258.1 Gene:Gzf1 / 311508 RGDID:1562321 Length:707 Species:Rattus norvegicus


Alignment Length:635 Identity:181/635 - (28%)
Similarity:249/635 - (39%) Gaps:145/635 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    66 KIKCENSSRTLRQLLPNALPEEPDSKVSISCPVATTDQAVQTTSWEPDRCTASVQTDAVTTTDAE 130
            |:||.:.|.|..||....|     ..|.:.....:..|.|:.:|......|.|.:.......||.
  Rat   115 KLKCLDLSETCLQLKKQML-----ESVLLELQNFSESQEVEASSGPQVSVTPSSKASVPAGEDAH 174

  Fly   131 QNTSLIKSTISVDLDYEGEGEVFDYELPD----EPVEKTTSL-------ILQVQGNLKDEKEVVF 184
            .| .|:.|:   |...|..|.....|.|.    |.::|...:       |.:..|.|..:|    
  Rat   175 SN-GLVDSS---DYPIERLGNGLSPETPSKKCKEKLDKKKDVAKPPFPKIRRASGRLAGKK---- 231

  Fly   185 TQTNVIYEGDDHELEQQIRECNLAIFEGVDNEAEIITVTAPQVTTRKSAAKLLTQQENDK---HQ 246
                |..|....:..:::||                     |..:.:.|||      |||   .|
  Rat   232 ----VFVEIPKKKYTRRLRE---------------------QQKSAEEAAK------NDKCPQDQ 265

  Fly   247 TPVGSKEEARELEK-EQVPQSAKRTSRRRGVVKQDVPATPPSDAEPSPKQHRLGTQRKLSAPRAG 310
            :|...:.||....| |..|.|.:|....:.|           :.|...::.:.|.::|.|     
  Rat   266 SPDNERVEAEPASKSEACPASVEREESLQKV-----------EGEKEEEEGKDGEEKKKS----- 314

  Fly   311 TVNGPSTT------------------SGAATTPELKYHCDRCNAGFAVEKSLMIHRRQKGCINRN 357
              |...|.                  .|.||  |:.|.||.|...||...:|..|:|......|:
  Rat   315 --NFQCTVCDKAFLYEKSFLKHIKYHHGVAT--EVVYRCDTCGQTFANRCNLKSHQRHVHSSERH 375

  Fly   358 YKCNECEKVF-----VSPDHLAEHQASHGAHNCPECGIRCDSKEALSKHMVQGHKRNLRNQCNIC 417
            :.|..|.|.|     |....|..|:.....|.|.:||....||.||..| .:.|..:....|..|
  Rat   376 FPCEMCAKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKTALRLH-ERTHTGDKPYGCTKC 439

  Fly   418 QKVFTMLSTLRDHMRIHTGEKPFVCNICGKSFTQNANLRQHKLRHSETKSFKCELCPHSFVTKAE 482
            ...|:..|.|:.|:|:||||:||||:.||..||||..|..||..|:..:.|.||.|..||.:|..
  Rat   440 DAKFSQPSALKTHLRVHTGERPFVCDECGARFTQNHMLIYHKRCHTGERPFMCETCGKSFASKEY 504

  Fly   483 LTSHARTHTGDKPFECEVCLARFTTSCSLAKHKRKHTGERPYACDLCPMRFTALNVLKNHRRTHT 547
            |..|.|.|||.|||:|||||..|....||.:|.:.|||||||.||.|..:||.:|.|:.|.|.||
  Rat   505 LKHHNRIHTGSKPFKCEVCLRTFAQRNSLYQHIKVHTGERPYCCDQCGKQFTQVNALQRHHRIHT 569

  Fly   548 GERPYVCPFCSKTFTQRGDCQMH--------------------------QRTHQGERIYICPVCN 586
            ||:||:|..|.:|||.:...:.|                          |:|.|.:..|..|..:
  Rat   570 GEKPYMCNACGRTFTDKSTLRRHTSIHDKNTPWKSFLVIVDGSPKNDEGQKTEQPDEEYASPKLS 634

  Fly   587 EEFKSMPEMRSHLAGHEQHDKRLVHFTFLSNKENGSGALEEELNEMTESA 636
            :...|..|..              ||..|...:....|::|  |..|::|
  Rat   635 DRLLSFGENS--------------HFNNLLEVQGNVPAVQE--NSSTDTA 668

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6654NP_650429.1 zf-AD 6..79 CDD:285071 5/12 (42%)
C2H2 Zn finger 331..354 CDD:275368 8/22 (36%)
COG5048 <357..570 CDD:227381 94/217 (43%)
C2H2 Zn finger 360..380 CDD:275368 7/24 (29%)
C2H2 Zn finger 385..406 CDD:275370 8/20 (40%)
C2H2 Zn finger 414..434 CDD:275368 7/19 (37%)
zf-H2C2_2 427..451 CDD:290200 14/23 (61%)
C2H2 Zn finger 442..490 CDD:275368 21/47 (45%)
C2H2 Zn finger 470..487 CDD:275368 7/16 (44%)
zf-H2C2_2 482..507 CDD:290200 15/24 (63%)
C2H2 Zn finger 498..518 CDD:275368 9/19 (47%)
zf-H2C2_2 510..534 CDD:290200 13/23 (57%)
C2H2 Zn finger 526..546 CDD:275368 9/19 (47%)
zf-H2C2_2 539..563 CDD:290200 13/23 (57%)
C2H2 Zn finger 554..574 CDD:275368 7/45 (16%)
C2H2 Zn finger 582..602 CDD:275368 3/19 (16%)
Gzf1NP_001101258.1 BTB 21..125 CDD:279045 4/9 (44%)
BTB 32..125 CDD:197585 4/9 (44%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 149..221 16/75 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 243..309 20/103 (19%)
C2H2 Zn finger 318..338 CDD:275370 1/19 (5%)
C2H2 Zn finger 349..370 CDD:275368 8/20 (40%)
C2H2 Zn finger 408..428 CDD:275368 8/20 (40%)
COG5048 <411..539 CDD:227381 58/128 (45%)
C2H2 Zn finger 436..456 CDD:275368 7/19 (37%)
zf-H2C2_2 448..473 CDD:290200 14/24 (58%)
C2H2 Zn finger 464..484 CDD:275368 10/19 (53%)
zf-H2C2_2 476..501 CDD:290200 10/24 (42%)
C2H2 Zn finger 492..512 CDD:275368 9/19 (47%)
zf-H2C2_2 504..529 CDD:290200 15/24 (63%)
C2H2 Zn finger 520..540 CDD:275368 9/19 (47%)
zf-H2C2_2 532..557 CDD:290200 14/24 (58%)
COG5048 544..>601 CDD:227381 24/56 (43%)
C2H2 Zn finger 548..568 CDD:275368 9/19 (47%)
zf-H2C2_2 560..584 CDD:290200 12/23 (52%)
C2H2 Zn finger 576..596 CDD:275368 6/19 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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