back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6654 and ZNF324

DIOPT Version :9

Sequence 1:	NP_650429.1	Gene:	CG6654 / 41831	FlyBaseID:	FBgn0038301	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	XP_005258770.1	Gene:	ZNF324 / 25799	HGNCID:	14096	Length:	558	Species:	Homo sapiens

Alignment Length:	520	Identity:	145/520 - (27%)
Similarity:	206/520 - (39%)	Gaps:	103/520 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 WEPDRCTASVQTDAVTTTDAEQNTSLIKSTISVDLDYEGEGEVFDYELPDEPVEKTTSLI----- 169
            |.|    :...|....||...:|..  ..:::.|.|..||   :....||.|...|||:.
Human    65 WVP----SGTDTTLSRTTYRRRNPG--SWSLTEDRDVSGE---WPRAFPDTPPGMTTSVFPVAGA 120

  Fly   170 ------LQVQGNLKDEKEVVFTQTNVIYEGDDHELEQQIRECNLAIFEGVDNEAEIITVTAPQVT 228
                  ||.|......:|...|..:|||..            .|.:..|....:..:.:|:|.
Human   121 CHSVKSLQRQRGASPSRERKPTGVSVIYWE------------RLLLGSGSGQASVSLRLTSPL-- 171

  Fly   229 TRKSAAKLLTQQENDKHQTPVGSKEEARELEKEQVPQSAKRTSRRRGVVKQDVP-----ATPPSD 288
                             :.|.|.:...:.|.:..:.....||..|:....|:||     :....:
Human   172 -----------------RPPEGVRLREKTLTEHALLGRQPRTPERQKPCAQEVPGRTFGSAQDLE 219

  Fly   289 AEPSPKQHRLGT-----QRKLSAPRAGTVN--GPSTTSGAATTPELKYHCDRCNAGFAVEKSLMI 346
            |......||:|.     .|.|......|.:  |.:..:|     |..:.|..|:..|.....|:.
Human   220 AAGGRGHHRMGAVWQEPHRLLGGQEPSTWDELGEALHAG-----EKSFECRACSKVFVKSSDLLK 279

  Fly   347 H-RRQKGCINRNYKCNECEKVFVSPDHLAEHQASHGA---HNCPECGIRCDSKEALSKHMVQGHK 407
            | |...|  .|.|:|.:|.|.|....||.:||..|..   :.||.||
Human   280 HLRTHTG--ERPYECAQCGKAFSQTSHLTQHQRIHSGETPYACPVCG------------------ 324

  Fly   408 RNLRNQCNICQKVFTMLSTLRDHMRIHTGEKPFVCNICGKSFTQNANLRQHKLRHSETKSFKCEL 472
                       |.|...|:|..|.||||.||.|.|:.|||:|:..:||.||:..|:..:.:.|..
Human   325 -----------KAFRHSSSLVRHQRIHTAEKSFRCSECGKAFSHGSNLSQHRKIHAGGRPYACAQ 378

  Fly   473 CPHSFVTKAELTSHARTHTGDKPFECEVCLARFTTSCSLAKHKRKHTGERPYACDLCPMRFTALN 537
            |...|...:.|..|.|||||:|||.|.:|.|.|:...||.||:|.||||:|:||..|...|:..:
Human   379 CGRRFCRNSHLIQHERTHTGEKPFVCALCGAAFSQGSSLFKHQRVHTGEKPFACPQCGRAFSHSS 443

  Fly   538 VLKNHRRTHTGERPYVCPFCSKTFTQRGDCQMHQRTHQGERIYICPVCNEEFKSMPEMRSHLAGH 602
            .|..|:..||||||:.|..|.|.|.:......|:|.|.||:.::|..|...|:..|.:..|...|
Human   444 NLTQHQLLHTGERPFRCVDCGKAFAKGAVLLSHRRIHTGEKPFVCTQCGRAFRERPALFHHQRIH 508

Fly 603 602
Human 509 508

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.