DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6654 and Y111B2A.10

DIOPT Version :9

Sequence 1:NP_650429.1 Gene:CG6654 / 41831 FlyBaseID:FBgn0038301 Length:639 Species:Drosophila melanogaster
Sequence 2:NP_499640.1 Gene:Y111B2A.10 / 176678 WormBaseID:WBGene00013734 Length:430 Species:Caenorhabditis elegans


Alignment Length:497 Identity:103/497 - (20%)
Similarity:182/497 - (36%) Gaps:124/497 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   151 EVFDYELPDEPVEKTTSLILQVQG------------NLKDEKEVVFTQTNVIYEGDDHELEQQIR 203
            |::||.:....:...||.......            |:.:.::::   ..:.:|.:|..:.:...
 Worm     2 EIYDYPMSYADLTPVTSCSSSSNSEADANNFSTKNKNVNEFQKLI---EELEFEPEDRRVPEVAE 63

  Fly   204 ECNLAIFEGVDNEAEIITVTAPQVTTRKSAAKLLTQQENDKHQTPVGS---KEEARELEKEQVPQ 265
            |     .|..|.|.|.:.:..|.  .||.|.:.| |:..::.....|.   :::|:||      |
 Worm    64 E-----VESEDEEEEDVQIKYPY--ERKDAYQDL-QERIERRLNDSGDEKLEQKAKEL------Q 114

  Fly   266 SAKRTSRRRGVVKQDVPATPPSDAEPSPKQHRLGTQRKLSAPRAGTVNGPSTTSGAATTPELKYH 330
            |..|.|:.:..|:|              ||.   .:..|..|.         |:|:..|      
 Worm   115 SLIRMSQSQWKVEQ--------------KQQ---LEDSLLKPH---------TAGSIFT------ 147

  Fly   331 CDRCNAGFAVEKSLMIHRRQKGCINR-NYKCNECEKVFVSPDHLAEHQASHGAH-NCPECGIRCD 393
            |..|:..|...::|.||..|...::| .::|..|.|.:....:|..|.|.|... .|..|.:...
 Worm   148 CVMCSKAFPNAEALQIHTDQVHDLSRLKHRCKLCGKAYKRKKNLDAHMALHLKEIQCDNCSLVFQ 212

  Fly   394 SKEALSKHMVQGHKRNL------RNQCNICQKVFTMLSTLRDHMRIHTGEK-------------- 438
            |:::|..|:::.|:.:.      :..|:||:::|...|...........||              
 Worm   213 SEKSLQSHIIRHHQEDADELEVWKAPCSICKELFPSTSVKTHEWYCKNREKIIEKQRVSKILKVQ 277

  Fly   439 -----PFVCNICGKSF--------TQNANLRQHKLRHSETKSFKCELCPHSFVTKAELTSHARTH 490
                 |.:..:...||        |...:.|.        ||  |::|..||.::..:..|....
 Worm   278 SLPSSPALSTVSYASFSSCQPGPITSPVSYRD--------KS--CQVCGESFASRQSMLRHVGRK 332

  Fly   491 TGDKPFECEVCLARFTTSCSLAKHKRKHTGERPYACDLCPMRFTALNVLKNHR-RTHTGERPYVC 554
            ..|...:..|...|:     ::....||    ||||..|..|||.:..|..|: |.|:....:.|
 Worm   333 HPDAKNDPNVTAVRY-----ISAESPKH----PYACIECGKRFTTVTALSTHKARVHSQSNRFEC 388

  Fly   555 PFCSKTFTQRGDCQMH-QRTHQGERIYICPVCNEEFKSMPEM 595
            ..|.|::....:.:.| :|.|:.:    .|......:.:|||
 Worm   389 TICHKSYPVPSELRKHIKRVHEKD----APKSRSALEELPEM 426

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6654NP_650429.1 zf-AD 6..79 CDD:285071
C2H2 Zn finger 331..354 CDD:275368 7/22 (32%)
COG5048 <357..570 CDD:227381 52/247 (21%)
C2H2 Zn finger 360..380 CDD:275368 6/19 (32%)
C2H2 Zn finger 385..406 CDD:275370 5/20 (25%)
C2H2 Zn finger 414..434 CDD:275368 5/19 (26%)
zf-H2C2_2 427..451 CDD:290200 5/50 (10%)
C2H2 Zn finger 442..490 CDD:275368 11/55 (20%)
C2H2 Zn finger 470..487 CDD:275368 4/16 (25%)
zf-H2C2_2 482..507 CDD:290200 4/24 (17%)
C2H2 Zn finger 498..518 CDD:275368 2/19 (11%)
zf-H2C2_2 510..534 CDD:290200 8/23 (35%)
C2H2 Zn finger 526..546 CDD:275368 8/20 (40%)
zf-H2C2_2 539..563 CDD:290200 7/24 (29%)
C2H2 Zn finger 554..574 CDD:275368 5/20 (25%)
C2H2 Zn finger 582..602 CDD:275368 4/14 (29%)
Y111B2A.10NP_499640.1 C2H2 Zn finger 148..169 CDD:275368 7/20 (35%)
zf-C2H2_8 151..221 CDD:292531 18/69 (26%)
C2H2 Zn finger 178..198 CDD:275368 6/19 (32%)
C2H2 Zn finger 204..224 CDD:275368 5/19 (26%)
C2H2 Zn finger 312..333 CDD:275368 5/20 (25%)
C2H2 Zn finger 359..380 CDD:275368 8/20 (40%)
C2H2 Zn finger 388..409 CDD:275368 5/20 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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