DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6654 and ZBTB42

DIOPT Version :9

Sequence 1:NP_650429.1 Gene:CG6654 / 41831 FlyBaseID:FBgn0038301 Length:639 Species:Drosophila melanogaster
Sequence 2:NP_001131073.1 Gene:ZBTB42 / 100128927 HGNCID:32550 Length:422 Species:Homo sapiens


Alignment Length:311 Identity:73/311 - (23%)
Similarity:101/311 - (32%) Gaps:120/311 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly   225 PQVTTRKSAAKLLTQQENDKHQTPVGSKEEARELEKEQVPQSAKRTSRRRGVVKQDVPATPPSDA 289
            |..:.|:..|:.|.:.|.|       |..|..|....:.|.|.              |..||..|
Human   210 PLCSQRQPGAQPLVKDERD-------SLSEQEESSSSRSPHSP--------------PKPPPVPA 253

  Fly   290 --------EPSP------KQHRLGTQRKLSAPRAGTVNGPSTTSGAATTPELKYHCDRCNAGFAV 340
                    :|.|      ::..||..|..|....|. .||...            |..|:..|..
Human   254 AKGLVVGLQPLPLSGEGSRELELGAGRLASEDELGP-GGPLCI------------CPLCSKLFPS 305

  Fly   341 EKSLMIHRRQKGCINRNYKCNECEKVFVSPDHLAEHQASHGAHNCPECGIRCDSKEALSKHMVQG 405
            ...|.:|      ::.:::..:..:..:|||.:|.        .||.||                
Human   306 SHVLQLH------LSAHFRERDSTRARLSPDGVAP--------TCPLCG---------------- 340

  Fly   406 HKRNLRNQCNICQKVFTMLSTLRDHMRIHTGEKPFVCNICGKSFTQNANLRQHKLRHSETKSFKC 470
                         |.|:...||:.|.|.|:||||:.|..|||||..:.||.:|.:          
Human   341 -------------KTFSCTYTLKRHERTHSGEKPYTCVQCGKSFQYSHNLSRHTV---------- 382

  Fly   471 ELCPHSFVTKAELTSHARTHTGDKPFECEVCLARFTTSCSLAKHKRK-HTG 520
                              .||.:||..|..|..|||.|..|.:|.|| |.|
Human   383 ------------------VHTREKPHACRWCERRFTQSGDLYRHVRKFHCG 415

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6654NP_650429.1 zf-AD 6..79 CDD:285071
C2H2 Zn finger 331..354 CDD:275368 5/22 (23%)
COG5048 <357..570 CDD:227381 44/165 (27%)
C2H2 Zn finger 360..380 CDD:275368 4/19 (21%)
C2H2 Zn finger 385..406 CDD:275370 4/20 (20%)
C2H2 Zn finger 414..434 CDD:275368 6/19 (32%)
zf-H2C2_2 427..451 CDD:290200 14/23 (61%)
C2H2 Zn finger 442..490 CDD:275368 9/47 (19%)
C2H2 Zn finger 470..487 CDD:275368 0/16 (0%)
zf-H2C2_2 482..507 CDD:290200 8/24 (33%)
C2H2 Zn finger 498..518 CDD:275368 10/20 (50%)
zf-H2C2_2 510..534 CDD:290200 6/12 (50%)
C2H2 Zn finger 526..546 CDD:275368
zf-H2C2_2 539..563 CDD:290200
C2H2 Zn finger 554..574 CDD:275368
C2H2 Zn finger 582..602 CDD:275368
ZBTB42NP_001131073.1 BTB_POZ_ZBTB42 1..129 CDD:349737
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 121..141
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 166..188
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 207..256 15/66 (23%)
COG5048 <292..>405 CDD:227381 44/195 (23%)
C2H2 Zn finger 296..316 CDD:275368 5/25 (20%)
C2H2 Zn finger 336..356 CDD:275368 10/48 (21%)
zf-H2C2_2 349..371 CDD:338759 12/21 (57%)
C2H2 Zn finger 364..384 CDD:275368 9/47 (19%)
C2H2 Zn finger 392..410 CDD:275368 8/17 (47%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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