Protein Alignment Mau2 and Mau2

DIOPT Version :10

• Sequence 1: NP_650428.1
• Gene: Mau2 / 41830
• FlyBaseID: FBgn0038300
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_001099547.2
• Gene: Mau2 / 290668
• RGDID: 1308759
• Length: 619
• Species: Rattus norvegicus
• Alignment Length: 601
• Identity: 297/601 - (49%)
• Similarity: 411/601 - (68%)
• Gaps: 13/601 - (2%)

  Fly     2 SASTSTSTAASQDACYISLLGLAEYFRTSQPPNIKKCIQCLQALFTFMPPSKVEARTHLQMGQIL 66
            :|:...:.|.:.::.|::|||.||:||||.||.|:.|:.||||:|.|.||.::|||||||:|.:|
  Rat    17 AAAAQAAQAEAAESWYLALLGFAEHFRTSSPPKIRLCVHCLQAVFPFKPPQRIEARTHLQLGSVL 81

  Fly    67 MAYTKNIDLARQHLEKAWSISEPLPNF-DVKFDTASLLAQLHLQTDRNSHQAKAMLRRAVELSQN 130
            ..:|||.:.||.||||||.||:.:|.| ||||:.||||::|:.| :.:...||.:||:|:::||.
  Rat    82 YHHTKNSEQARSHLEKAWLISQQIPQFEDVKFEAASLLSELYCQ-ENSVDAAKPLLRKAIQISQQ 145

  Fly   131 NVYWHCKLLLQLAQIHASDREYSLASELLAVGAESADEASATYLKVLFLLSRAMILMIERKTNDV 195
            ..||||:||.||||:|..:::...|.:||.||||.|....:.|.:.|||||:.|:|::|||..:|
  Rat   146 TPYWHCRLLFQLAQLHTLEKDLVSACDLLGVGAEYARVVGSEYTRALFLLSKGMLLLMERKLQEV 210

  Fly   196 LALLNSAGQIIDNNIPNPHQKEYLKVFFLVLQVCYYLALGQVKTVKPSLKQLQMSIQTIMAPNWP 260
            ..||...|||::|...||.|||.|:||||||||.:||..||||:|||.|||||..||||...:
  Rat   211 HPLLTLCGQIVENWQGNPIQKESLRVFFLVLQVTHYLDAGQVKSVKPCLKQLQQCIQTISTLH-- 273

  Fly   261 SDEAIFGANQLEMFVWLPKEQLYVLVYLVTVSHSMMAGYMDKAQKYTEKALTQIEKLKQQEDKPI 325
             |:.|..:|..::|.|||||.:.||||||||.|||.|||::||||||:|||.|:||||..:..||
  Rat   274 -DDEILPSNPADLFHWLPKEHMCVLVYLVTVMHSMQAGYLEKAQKYTDKALMQLEKLKMLDCSPI 337

  Fly   326 LSVFKVILLEHIVMCRMVMGNRELAIREIAAARDVCMAAPQRSLLRRHSAQLHCLIGLYSMSTNL 390
            ||.|:|||||||:|||:|.|::..|::||:....:|..:|:  |...|:||||.|:|||.:|.|.
  Rat   338 LSSFQVILLEHIIMCRLVTGHKATALQEISQVCQLCQQSPR--LFSNHAAQLHTLLGLYCVSVNC 400

  Fly   391 FEHAERQFVVCVSETSERDLKLFANLNLAIIYLR--TKRDTDLKQILDAVSTENTHTYSSQALMG 453
            .::||.||...:..|:.::|..|...|||.:|:|  .:....|..:|:.::.:::...||..|..
  Rat   401 MDNAEAQFTTALRLTNHQELWAFIVTNLASVYIREGNRHQEVLYSLLERINPDHSFPVSSHCLRA 465

  Fly   454 GFYYVQGLHAFHKNSFHEAKRFLRETLKMANAEDLNRLTSCSLVLLSHVFLSIGNSKESMNMVTP 518
            ..:||:||.:|.:..::||||||||||||:|||||||||:||||||.|:|..:||.:||.|||.|
  Rat   466 AAFYVRGLFSFFQGRYNEAKRFLRETLKMSNAEDLNRLTACSLVLLGHIFYVLGNHRESNNMVVP 530

  Fly   519 AMQLASKIPDIHVQLWGSAILKDLHRMSKDVQHEKDAYANHVKYSENLIADQRKCVQSAHHELVN 583
            ||||||||||:.||||.||:|:||::...:.....:|...|..:|:.|:.|..:......|.|:.
  Rat   531 AMQLASKIPDMSVQLWSSALLRDLNKACGNAMDAHEAAQMHQNFSQQLLQDHIEACSLPEHNLIT 595

  Fly   584 WFQGDPPV----TSGP 595
            |..|.|||    .:||
  Rat   596 WTDGPPPVQFQAQNGP 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mau2	NP_650428.1	Cohesin_load	16..545	CDD:463053	281/531 (53%)
Mau2	NP_001099547.2	Cohesin_load	31..560	CDD:463053	281/531 (53%)
		TPR repeat	71..100	CDD:276809	18/28 (64%)
		TPR repeat	105..142	CDD:276809	17/37 (46%)
		TPR repeat	151..174	CDD:276809	9/22 (41%)
		TPR repeat	385..413	CDD:276809	13/27 (48%)
		TPR repeat	417..450	CDD:276809	9/34 (26%)
		TPR repeat	465..493	CDD:276809	12/27 (44%)