Protein Alignment Spn88Eb and SERPINB11

DIOPT Version :10

• Sequence 1: NP_650427.1
• Gene: Spn88Eb / 41829
• FlyBaseID: FBgn0038299
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_536723.2
• Gene: SERPINB11 / 89778
• HGNCID: 14221
• Length: 392
• Species: Homo sapiens
• Alignment Length: 420
• Identity: 118/420 - (28%)
• Similarity: 199/420 - (47%)
• Gaps: 75/420 - (17%)

  Fly    40 DFSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGWALNKQQVLVSYT 104
            :|.|.:.|::.......|:|||..|...||.:....:..:||.:|.:.|:.           |:|
Human    10 EFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHF-----------SHT 63

  Fly   105 LAQRQDEFRWRQSP-------------MELSSANRIFVDRTINVSNKFNTLLYGATKEL------ 150
            :...:..|  :.||             :|.|..|:...:.|::::|:    ||| ||.:
Human    64 VDSLKPGF--KDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANR----LYG-TKTMAFHQQY 121

  Fly   151 ---------------DFKNDPETGLKEINDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKG 200
                           ||:...|...|.||.|:.:||:.::.::.....|.|.:::||.||.|.||
Human   122 LSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIYFKG 186

  Fly   201 QWLSQFKVEETALKPFFINEREQEMVYMMHKTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHIST 265
            ||.::|:|.||...||.::|.:...|.||::.|.||:...:..|.|:::|||
Human   187 QWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPY------------- 238

  Fly   266 PESKSDISMIIILPNSNKISLNRVISRLNADSVKKWFERA--LPQKIELSLPKFQFEQRLELTPI 328
              ..:.:||||:|| ....:|.::..:||:.:..:|...:  :.:::|:.||:|:.|.:.||..:
Human   239 --VNNKLSMIILLP-VGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSL 300

  Fly   329 LSLMGVNTMFTRNATFGDLTA-DPI-SLVIDDAQHLAKIKVDEVGSTAAAATILLVSRSSRQPDP 391
            |..:||..:|  |....||:. .|. .|.:..|.|.:.:.|.|.|:.|||||...::..| .|..
Human   301 LKSLGVTDLF--NQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKS-LPMR 362

  Fly   392 TKFNCNHPFVFLIYDEKVDTILFAGVYSDP 421
            .:|..||||:|.|.....:||||.|..:.|
Human   363 AQFKANHPFLFFIRHTHTNTILFCGKLASP 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	serpin_crustaceans_chelicerates_insects	34..421	CDD:381059	117/418 (28%)
SERPINB11	NP_536723.2	serpinB11_epipin	1..392	CDD:381036	117/418 (28%)
		RCL. /evidence=ECO:0000250	341..365		9/24 (38%)