Protein Alignment Spn88Eb and SERPINB12

DIOPT Version :9

• Sequence 1: NP_650427.1
• Gene: Spn88Eb / 41829
• FlyBaseID: FBgn0038299
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: XP_005266835.2
• Gene: SERPINB12 / 89777
• HGNCID: 14220
• Length: 437
• Species: Homo sapiens
• Alignment Length: 461
• Identity: 119/461 - (25%)
• Similarity: 202/461 - (43%)
• Gaps: 88/461 - (19%)

  Fly    22 KPELSFLNEFSQIFKGERDFSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQ 86
            :|::........:......|...|.::|.:.....|:||||.|...||.:....:...:..::.:
Human     4 RPQIVISFTMDSLVTANTKFCFDLFQEIGKDDRHKNIFFSPLSLSAALGMVRLGARSDSAHQIDE 68

  Fly    87 ALNLG-------------WALNKQQVLVSYTLAQRQDEFRWRQSPME------------------ 120
            .|:..             ...|||:||...:|..::.    ...|::
Human    69 VLHFNEFSQNESKEPDPCLKSNKQKVLADSSLEGQKK----TTEPLDQQAGSLNNESGLVSCYFG 129

  Fly   121 --LSSANRIFVDRTINVSNKFNTLLYG--------------------ATKELDFKNDPETGLKEI 163
              ||..:||..|.|::::|:    |||                    ..:.:||:.:||...:||
Human   130 QLLSKLDRIKTDYTLSIANR----LYGEQEFPICQEYLDGVIQFYHTTIESVDFQKNPEKSRQEI 190

  Fly   164 NDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKPFFINEREQEMVYM 228
            |.|:..::..:|:::.|.:.|...|:|||.||.|.|.:|.:.|..|.|...||.:|..|.:.|.|
Human   191 NFWVECQSQGKIKELFSKDAINAETVLVLVNAVYFKAKWETYFDHENTVDAPFCLNANENKSVKM 255

  Fly   229 MHKTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPNSNKIS---LNRVI 290
            |.:.|.:::...|.:::||:::.|               :|..:||.::||:.:|.:   |..:.
Human   256 MTQKGLYRIGFIEEVKAQILEMRY---------------TKGKLSMFVLLPSHSKDNLKGLEELE 305

  Fly   291 SRLNADSVKKW--FERALPQKIELSLPKFQFEQRLELTPILSLMGVNTMFTRNATFGDLTA---D 350
            .::..:.:..|  .|....:.:.||.|:|..|...:|..||..||:..:|  :.|..|||.   .
Human   306 RKITYEKMVAWSSSENMSEESVVLSFPRFTLEDSYDLNSILQDMGITDIF--DETRADLTGISPS 368

  Fly   351 PISLVIDDAQHLAKIKVDEVGSTAAAATILLVSRSSRQPDPTKFNCNHPFVFLIYDEKVDTILFA 415
            | :|.:....|...::|||.|:.|||||..:||..|.: ...:||.||||:|.|...|..||||.
Human   369 P-NLYLSKIIHKTFVEVDENGTQAAAATGAVVSERSLR-SWVEFNANHPFLFFIRHNKTQTILFY 431

  Fly   416 GVYSDP 421
            |....|
Human   432 GRVCSP 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	117/441 (27%)
SERPINB12	XP_005266835.2	ovalbumin_like	16..437	CDD:239014	117/447 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820