DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn88Eb and zgc:173729

DIOPT Version :9

Sequence 1:	NP_650427.1	Gene:	Spn88Eb / 41829	FlyBaseID:	FBgn0038299	Length:	426	Species:	Drosophila melanogaster
Sequence 2:	NP_001103200.1	Gene:	zgc:173729 / 798311	ZFINID:	ZDB-GENE-071004-64	Length:	439	Species:	Danio rerio

Alignment Length:	446	Identity:	124/446 - (27%)
Similarity:	195/446 - (43%)	Gaps:	82/446 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 FSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNL-------------GW 92
            |||.|.|:|.....|||:|:||.|..:||.:....:...|..::.:.|..             ..
Zfish    11 FSLNLFKKISGGNASGNVFYSPVSISSALAMVSLGAKGNTADQMFKVLGFNNPPKPGGATPTPAQ 75

  Fly    93 ALNKQQVLVS-------YTLAQRQ---------------------------------DEFRWRQS 117
            |..|.|:...       ..|.|.|                                 .|.....:
Zfish    76 ATQKPQITCGVKSQHEPQALQQPQKFELPADLKKCPAQPVPGQKAEEQIHSSFNKFMSELNKPGA 140

  Fly   118 PMELSSANRIFVDRTINVSNKF----NTLLYGATKELDFKNDPETGLKEINDWIADKTHNQIRDM 178
            |..||.|||::.::|.....||    .|......:::||||..|.....||.|:...|..:|:|:
Zfish   141 PYVLSLANRLYGEQTYQFLEKFLSDAKTYYAAGLEKVDFKNKSEASRVNINKWVEKNTQEKIKDL 205

  Fly   179 LSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKPFFINEREQEMVYMMHKTGAFKMTIDEGL 243
            |.|..|...|.|||.||.|.||.|..:|..|.|....|.:|:.:.:.|.|||:...|.:.....:
Zfish   206 LPSGAIDAMTRLVLVNAIYFKGNWEKKFTKEATRDGQFKLNKNQTKPVKMMHQKARFSLASIPEM 270

  Fly   244 QSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPNSNK---ISLNRVISRLNADSVKKWFERA 305
            .||:::|||               :..::||:||||:..:   ..|.::...|..:.:.:|.:.:
Zfish   271 NSQVLELPY---------------AGKNLSMLIILPDQIEDATTGLQKLEKALTYEKLMEWTKPS 320

  Fly   306 L--PQKIELSLPKFQFEQRLELTPILSLMGVNTMFTRNATFGDLTADPIS--LVIDDAQHLAKIK 366
            :  .|::::|||||:.||..::..:|..||:..:|.....  :||....|  ||:....|.|.::
Zfish   321 MMCQQEVQVSLPKFKTEQTYDMKSLLVSMGMEDVFDPQKV--NLTGMSSSNDLVLSKVIHKAFVE 383

  Fly   367 VDEVGSTAAAATILLVSRSSRQPDPTK-FNCNHPFVFLIYDEKVDTILFAGVYSDP 421
            |:|.|:.|||||.::.:.:|....|.| |..:|||:|.|.....:.|||.|.:|.|
Zfish   384 VNEEGTEAAAATGVIATLTSMPLSPPKTFTADHPFIFFIRHNPTNAILFYGRFSSP 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	122/441 (28%)
zgc:173729	NP_001103200.1	SERPIN	4..439	CDD:294093	123/444 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820