DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn88Eb and zgc:174259

DIOPT Version :9

Sequence 1:	NP_650427.1	Gene:	Spn88Eb / 41829	FlyBaseID:	FBgn0038299	Length:	426	Species:	Drosophila melanogaster
Sequence 2:	XP_021331992.1	Gene:	zgc:174259 / 791587	ZFINID:	ZDB-GENE-080213-10	Length:	410	Species:	Danio rerio

Alignment Length:	436	Identity:	115/436 - (26%)
Similarity:	189/436 - (43%)	Gaps:	83/436 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LDKPELSFLNEFSQIFKGERDFSLALMKQIREI--YPSGNLFFSPFSTYNALLLAYFSSSEQTER 82
            |.:|.:|  .:...:.....||:..|.|::.|.  |.|.|:||||||...||       ||
Zfish    24 LQQPPIS--AKLPSLINMNNDFAFHLYKRLIESPDYQSKNIFFSPFSVSMAL-------SE---- 75

  Fly    83 ELAQALNLG-WALNKQQVL--VSYTLA--QRQDEFRWRQSPMELSSANRIFVDRTINVSNKFNTL 142
                 |:|| ....|||:|  :.|:.|  ..::..:...|.:| ...||..||  |:|    .|.
Zfish    76 -----LSLGAGGDTKQQLLSGIGYSSAIFSTEEMHQLFHSLLE-DIGNRTGVD--IDV----GTA 128

  Fly   143 LYGATK--------------------ELDFKNDPETGLKEINDWIADKTHNQIRDMLSSEEITPH 187
            ||.:.:                    .:|| :..|| :.:||.::.:|||.:|...:  :::...
Zfish   129 LYASDRFKPHSKFLEDMKEFYHSDGFTVDF-SVKET-VDQINKYVEEKTHGKINQAV--DDLDAD 189

  Fly   188 TMLVLANAAYMKGQWLSQFKVEETALKPFFINEREQEMVYMMHKTGAFKMTIDEGLQSQIIKLPY 252
            |.:||....|.||:|...|..:.|:...|.|:::....|.|||:....|:..|..|.::::.|.|
Zfish   190 TFMVLLTYIYFKGKWDKPFNPKTTSESTFHIDDKTTVPVQMMHQYERLKVYYDAELSTKVLCLDY 254

  Fly   253 RTIYKSKETHISTPESKSDISMIIILPNSNK-----ISLNRVISRLNADSVKKWFERALPQKIEL 312
                            ....||.:.:|:.:.     ..|...:||   ..|:||......:|:::
Zfish   255 ----------------NDSFSMFLAVPDVHMGRKTIKDLEMTVSR---QHVEKWRRSVSERKVDI 300

  Fly   313 SLPKFQFEQRLELTPILSLMGVNTMFTRNATFGDLTADPISLVIDDAQHLAKIKVDEVGSTAAAA 377
            .:||...:....|..||..||:..||:..|.|..::.:.|  .:....|.|.:.:||.|:||||.
Zfish   301 YVPKLSLKTSYSLKDILKGMGMADMFSDKADFTGVSEEKI--YVSKVLHKATLDIDEKGTTAAAV 363

  Fly   378 TILLVSRSSRQPDPTKFNCNHPFVFLIYDEKVDTILFAGVYSDPRQ 423
            |.:.:...|..| .:..:.:.||:..|.|:..|.|||.|...:|.:
Zfish   364 TTVHLRFMSYSP-MSDLSFDRPFMIFITDQTNDNILFVGKVVNPNE 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	111/412 (27%)
zgc:174259	XP_021331992.1	alpha-1-antitrypsin_like	39..403	CDD:239011	111/412 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.100