DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn88Eb and Serpine3

DIOPT Version :9

Sequence 1:	NP_650427.1	Gene:	Spn88Eb / 41829	FlyBaseID:	FBgn0038299	Length:	426	Species:	Drosophila melanogaster
Sequence 2:	XP_006252257.2	Gene:	Serpine3 / 691375	RGDID:	1585042	Length:	413	Species:	Rattus norvegicus

Alignment Length:	429	Identity:	85/429 - (19%)
Similarity:	159/429 - (37%)	Gaps:	121/429 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 LNEFSQIFKGERDFSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGW 92
            |:|...:.|.|  |:|.|.:.........|...||.|...:|.:..|::...|..:||:||
  Rat    24 LSEGLWLLKTE--FALHLYQSAAAETNGTNFVISPASVSLSLEILQFAARGNTGWQLAEAL---- 82

  Fly    93 ALNKQQVLVSYTLAQRQDEFRWRQSPMELSSANRIFVDRTINVSNKFNTLLYGATKELDFKNDPE 157
                     .||:          |.|......:.:::  |::.|::      |...||......:
  Rat    83 ---------GYTV----------QDPRVREFLHTVYI--TLHNSSQ------GIGMELACTLFMQ 120

  Fly   158 TG-------LKEINDW------IADKTHNQIRDMLSSEEITP------------------HTMLV 191
            ||       :::::.|      :||.:......|.:|:..|.                  .|.|.
  Rat   121 TGTSLSPCFVEQVSRWANSSLELADFSEPNTTTMEASKGTTRPSTGEGPGSPLWGRAGALSTQLS 185

  Fly   192 LANAAYMKGQWLSQFKVEETALKPFFINEREQEMVYMMHKTGAFKMTIDEGLQSQIIKLPYRTIY 256
            :.:....:..|..:|  ...||:|             :..|.|..:.:......|:.::.|.. :
  Rat   186 IVSTMTFQSSWQQRF--SSVALQP-------------LPFTCAHGLVLQVPAMHQVAEVSYGQ-F 234

  Fly   257 KSKETHISTPESKSDI----------SMIIILPNSNKISLNRVISRLNADSVKKWFERALPQKIE 311
            :....|      |.|:          |::::||......|:.:...|.|..:..|..|....:::
  Rat   235 QDAAGH------KVDVLELLYLGRVASLLLVLPQDKGTPLDHIEPHLTARVIHLWTTRLKRARMD 293

  Fly   312 LSLPKFQFEQRLELTPILSLMGVNTMFTRNATFGDLTADPI-----------SLVIDDAQHLAKI 365
            :.||:|:.:.:.:|..||...|:..:|           ||:           ...:.:..|.||:
  Rat   294 VFLPRFRIQNQFDLKSILRSWGITDLF-----------DPLKANLKGISGRDGFYVSEVTHKAKM 347

  Fly   366 KVDEVGSTAAAATILLVSRSSRQPDPTKFNCNHPFVFLI 404
            ::.|.|:.:.|||.:|:.|.||.|   .|..:.||:||:
  Rat   348 ELSEEGTKSCAATAVLLLRRSRTP---AFKADRPFIFLL 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	82/420 (20%)
Serpine3	XP_006252257.2	serpin	20..400	CDD:422956	85/429 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.110