Protein Alignment Spn88Eb and SERPINA7

DIOPT Version :9

• Sequence 1: NP_650427.1
• Gene: Spn88Eb / 41829
• FlyBaseID: FBgn0038299
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: XP_006724746.1
• Gene: SERPINA7 / 6906
• HGNCID: 11583
• Length: 425
• Species: Homo sapiens
• Alignment Length: 441
• Identity: 109/441 - (24%)
• Similarity: 190/441 - (43%)
• Gaps: 75/441 - (17%)

  Fly    15 VTIAALDKPELSFLNEFSQIFKGERDFSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQ 79
            ||.....:|..: |.:.|.|   ..||:..|.::.....|..|:||||.|...||::..|.:...
Human    27 VTACHSSQPNAT-LYKMSSI---NADFAFNLYRRFTVETPDKNIFFSPVSISAALVMLSFGACCS 87

  Fly    80 TERELAQALNLGWALNKQQVLVSYTLAQRQDEFR-------WRQSPMELSSANRIFVDRTINVSN 137
            |:.|:.:.|...        |....:.:.|..|:       :.:..:||...|.:|:.:.:....
Human    88 TQTEIVETLGFN--------LTDTPMVEIQHGFQHLICSLNFPKKELELQIGNALFIGKHLKPLA 144

  Fly   138 KF----NTLLYGATKELDFKNDPETGLKEINDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYM 198
            ||    .||........||.| .....:|||..:..:|..::..::  :::.|:|::||.|..:.
Human   145 KFLNDVKTLYETEVFSTDFSN-ISAAKQEINSHVEMQTKGKVVGLI--QDLKPNTIMVLVNYIHF 206

  Fly   199 KGQWLSQF---KVEETALKPFFINEREQEMVYMMHKTGAFKMTIDEGLQSQIIKLPYRTIYKSKE 260
            |.||.:.|   |.|:::  .|.|::.....|.|||:...:...:|..|...::::.|
Human   207 KAQWANPFDPSKTEDSS--SFLIDKTTTVQVPMMHQMEQYYHLVDMELNCTVLQMDY-------- 261

  Fly   261 THISTPESKSDISMIIILPNSNKISLNRVISRLNADSVKKWFERALPQK--IELSLPKFQFEQRL 323
                   ||:.:: :.:||...:  :..|.:.:::.::|||  ..|.||  ::|.:|||......
Human   262 -------SKNALA-LFVLPKEGQ--MESVEAAMSSKTLKKW--NRLLQKGWVDLFVPKFSISATY 314

  Fly   324 ELTPILSLMGVNTMFTRNATFGDLTAD--------PISLVI-DDAQHLAKIKVDEVGSTAAAATI 379
            :|...|..||:...::.||.|..||.|        |...|: ..|.|.|.:.:.|.|:.|||...
Human   315 DLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNRPAGFVLPTQAAHKAVLHIGEKGTEAAAVPE 379

  Fly   380 LLVSRSSRQPDPTKFNCNHP-------FVFLIYDEKVDTILFAGVYSDPRQ 423
            :   ..|.||:.|..   ||       |:.||.:....:|||.|...:|.:
Human   380 V---ELSDQPENTFL---HPIIQIDRSFMLLILERSTRSILFLGKVVNPTE 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	102/412 (25%)
SERPINA7	XP_006724746.1	alpha-1-antitrypsin_like	46..419	CDD:239011	102/411 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010