Protein Alignment Spn88Eb and Serpina12

DIOPT Version :9

• Sequence 1: NP_650427.1
• Gene: Spn88Eb / 41829
• FlyBaseID: FBgn0038299
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_080811.1
• Gene: Serpina12 / 68054
• MGIID: 1915304
• Length: 413
• Species: Mus musculus
• Alignment Length: 436
• Identity: 109/436 - (25%)
• Similarity: 203/436 - (46%)
• Gaps: 56/436 - (12%)

  Fly     9 LALLPVVTIAAL----DKPELSFLNEFSQIFKGERD----------FSLALMKQIREIYPSGNLF 59
            |.|..::|:..|    |.|::.......|.::|::|          |...|::::....|.||:|
Mouse     9 LFLAGLLTVKGLLQDRDAPDMYDSPVRVQEWRGKKDARQLARHNMEFGFKLLQRLASNSPQGNIF 73

  Fly    60 FSPFSTYNALLLAYFSSSEQTERELAQALNL----GWALNKQQVLVSYTLAQRQDEFRWRQSPME 120
            .||.|...|..:....:...|..|:.:..|.    .|.::.....:.:.|.|..::       .:
Mouse    74 LSPLSISTAFSMLSLGAQNSTLEEIREGFNFKEMSNWDVHAAFHYLLHKLNQETED-------TK 131

  Fly   121 LSSANRIFVDRTINVSNKFNTL---LYGATKELDFKNDPETGLKEINDWIADKTHNQIRDMLSSE 182
            ::..|.:|:|:.:....:|..|   :|.|...|....|.|...|:||.:|:.|||::|::|:.|
Mouse   132 MNLGNALFMDQKLRPQQRFLNLAKNVYDADMVLTNFQDLENTQKDINRYISQKTHSRIKNMVKS- 195

  Fly   183 EITPHTMLVLANAAYMKGQWLSQFKVEETALKPFFINEREQEMVYMMHKTGAFKMTIDEGLQSQI 247
             |.|.|:::|.|..|.:|:|..:|..::|..:.|||.:.:...|.||.:.|.:.|..|..|...|
Mouse   196 -IDPGTVMILTNYIYFRGRWQYEFDPKQTKEEEFFIEKGKTVKVPMMFQRGLYDMAYDSQLSCTI 259

  Fly   248 IKLPYRTIYKSKETHISTPESKSDISMIIILPNSNKISLNRVISRLNADSVKKWFERALPQKIEL 312
            :::|||                .:|:...:||::.|:.|  :...|.||...||......:.:::
Mouse   260 LEIPYR----------------GNITATFVLPDNGKLKL--LEQGLQADIFAKWKSLLSKRVVDV 306

  Fly   313 SLPKFQFEQRLELTPILSLMGVNTMFTRNATFGDLT--ADPISLVIDDAQHLAKIKVDEVGSTAA 375
            .:||.:......:..:||.:|::.:|..|   ||||  :...||.:.:|.|.|::|:||.|...|
Mouse   307 WVPKLRISSTYNMKKVLSRLGISKIFEEN---GDLTRISSHRSLKVGEAVHKAELKMDEKGMEGA 368

  Fly   376 AATILLVSRSSRQPDPTKFNCNHPFVFLIYDEKVDTILFAGVYSDP 421
            |.:   .:::.....|.....:.||:.:||:..:.:::|.....||
Mouse   369 AGS---GAQTLPMETPRHMKLDRPFLMMIYENFMPSMVFLARIYDP 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	100/399 (25%)
Serpina12	NP_080811.1	alpha-1-antitrypsin_like	51..408	CDD:239011	98/389 (25%)
		Reactive center loop. /evidence=ECO:0000250|UniProtKB:Q8IW75	364..382		3/20 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010