Protein Alignment Spn88Eb and SERPINE3

DIOPT Version :10

• Sequence 1: NP_650427.1
• Gene: Spn88Eb / 41829
• FlyBaseID: FBgn0038299
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_001094790.1
• Gene: SERPINE3 / 647174
• HGNCID: 24774
• Length: 424
• Species: Homo sapiens
• Alignment Length: 421
• Identity: 97/421 - (23%)
• Similarity: 166/421 - (39%)
• Gaps: 81/421 - (19%)

  Fly    28 LNEFSQIFKGERDFSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGW 92
            |.|...:.|.|  |:|.|.:.:.......|...||......|.:..|.:...|.::||.|  ||:
Human    22 LREGMTLLKTE--FALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADA--LGY 82

  Fly    93 ALNKQQV-----LVSYTLAQRQDEFRWRQSPMELSSANRIFVDRTINVSNKF-NTLLYGATKELD 151
            .::.::|     .|..||....     :.:.|||:.:  :||.....:|..| ..:.:.|...|:
Human    83 TVHDKRVKDFLHAVYATLPTSS-----QGTEMELACS--LFVQVGTPLSPCFVEHVSWWANSSLE 140

  Fly   152 FKNDPETGLKEINDWIADKTHNQIRDMLSS-----------EEIT-PHTMLVLANAAYMKGQWLS 204
                 ...|.|.|......:....|:....           |::: ....|||.:....:|.|..
Human   141 -----PADLSEPNSTAIQTSEGASRETAGGGPSEGPGGWPWEQVSAAFAQLVLVSTMSFQGTWRK 200

  Fly   205 QFKVEETALKPFFINEREQEMVYMMHKT-----GAFKMTIDEGLQSQIIKLPYRTIYKSKETHIS 264
            :|...:|.:.||.........|.|||:|     |.|:.|  .|.|..:::|||
Human   201 RFSSTDTQILPFTCAYGLVLQVPMMHQTTEVNYGQFQDT--AGHQVGVLELPY------------ 251

  Fly   265 TPESKSDISMIIILPNSNKISLNRVISRLNADSVKKWFERALPQKIELSLPKFQFEQRLELTPIL 329
               ..|.:|:.::||......|:.:...|.|.::..|.......::::.||:|:.:.:..|..||
Human   252 ---LGSAVSLFLVLPRDKDTPLSHIEPHLTASTIHLWTTSLRRARMDVFLPRFRIQNQFNLKSIL 313

  Fly   330 SLMGVNTMFTRNATFGDLTADPI-----------SLVIDDAQHLAKIKVDEVGSTAAAATILLVS 383
            :..||..:|           ||:           ...:.:|.|.|||:|.|.|:.|:.||.||:.
Human   314 NSWGVTDLF-----------DPLKANLKGISGQDGFYVSEAIHKAKIEVLEEGTKASGATALLLL 367

  Fly   384 RSSRQPDPTKFNCNHPFVFLIYDEKVDTILF 414
            :.||.|   .|..:.||::.:.:......:|
Human   368 KRSRIP---IFKADRPFIYFLREPNTGITVF 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	serpin_crustaceans_chelicerates_insects	34..421	CDD:381059	95/415 (23%)
SERPINE3	NP_001094790.1	serpinE3	18..400	CDD:381040	97/421 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	143..174		4/30 (13%)