DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn88Eb and serpind1

DIOPT Version :9

Sequence 1:	NP_650427.1	Gene:	Spn88Eb / 41829	FlyBaseID:	FBgn0038299	Length:	426	Species:	Drosophila melanogaster
Sequence 2:	NP_001015716.1	Gene:	serpind1 / 548433	XenbaseID:	XB-GENE-6085731	Length:	484	Species:	Xenopus tropicalis

Alignment Length:	414	Identity:	109/414 - (26%)
Similarity:	190/414 - (45%)	Gaps:	58/414 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 QIFKGE----------RDFSLALMKQIR-EIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQ 86
            ::|:|:          .:|...|.:.|: ....|.|:..:|.....|:......:..|.   |.|
Frog   101 ELFQGKTRVQRLSIINANFGFNLYRAIKNNTDASDNILLAPVGISTAMATISLGTKGQA---LDQ 162

  Fly    87 AL-NLGW-----ALNKQQVLVSYTLAQRQDE--FRWRQSPMELSSANRIFVDRTINVSNKFNTLL 143
            .| .||:     |.:|.::|..:.:.::...  || |.....|.|.|.|:|.:...:...|...|
Frog   163 VLFTLGFKNFINASSKYEILTLHNVFRKLTHRLFR-RNFGYTLRSVNDIYVKKDFVIREPFKNNL 226

  Fly   144 ----YGATKELDFKNDPETGLKEINDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLS 204
                :...:.:||.:  :..|.:.|..|...|...|::.|::  :.|..:::|.|..|.||.|.:
Frog   227 KNYYFAEAQMVDFGS--KDFLTKANKRIQQLTKGLIKEALTN--VDPALLMLLVNCIYFKGTWEN 287

  Fly   205 QFKVEETALKPFFINEREQEMVYMMHKTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESK 269
            :|.||.|....|.:||:|...|.||...|.|.:..|..|...:::|||                .
Frog   288 KFPVEYTQNMNFRLNEKELVKVPMMKTKGNFLVAADPELDCAVLQLPY----------------V 336

  Fly   270 SDISMIIILPNSNKISLNRVISR-LNADSVKKWFERALPQKIELSLPKFQFEQRLELTPILSLMG 333
            .:|||:|:||  :|:|..:::.: ::...|::|......:..|:.||:|:.|:...|..:||.||
Frog   337 GNISMLIVLP--HKLSGMKLLEKQISPQVVERWQNIMTNRTREVFLPRFKLEKSYNLQEVLSNMG 399

  Fly   334 VNTMFTRNATFGDLT-ADPISLVIDDAQHLAKIKVDEVGSTAAAATILLVSRSSRQPDPTKFNCN 397
            |..:||.    ||.: ....::.|...||...|.|:|.|:.|||.|::.....|.|   .:|..:
Frog   400 VTDLFTH----GDFSGVSDKNMNIGLFQHQGTITVNEEGTEAAAVTVVGFMPLSTQ---ARFVAD 457

  Fly   398 HPFVFLIYDEKVDTILFAGVYSDP 421
            .||:||||:.:.:.::|.|..::|
Frog   458 RPFLFLIYEHRTNCLIFMGRVANP 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	107/405 (26%)
serpind1	NP_001015716.1	serpinD1_HCF2	38..484	CDD:381004	109/414 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010