Protein Alignment Spn88Eb and SERPINF2

DIOPT Version :10

• Sequence 1: NP_650427.1
• Gene: Spn88Eb / 41829
• FlyBaseID: FBgn0038299
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: XP_005256758.2
• Gene: SERPINF2 / 5345
• HGNCID: 9075
• Length: 507
• Species: Homo sapiens
• Alignment Length: 388
• Identity: 96/388 - (24%)
• Similarity: 175/388 - (45%)
• Gaps: 47/388 - (12%)

  Fly    41 FSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGWALNKQQVLVSYTL 105
            |:..|...:.:.....||..||.|...||......:...|.:.|.|.|:.|     ....:.:.|
Human   105 FTADLFSLVAQTSTCPNLILSPLSVALALSHLALGAQNHTLQRLQQVLHAG-----SGPCLPHLL 164

  Fly   106 AQRQDEFRWRQSPMELSSANRIFVDRTINVSNKF---NTLLYGATKELDFKNDPETGLKEINDWI 167
            ::...:.    .|.....|.|:::.:...:...|   :..|:|| |.:......|..|..||.|:
Human   165 SRLCQDL----GPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGA-KPVSLTGKQEDDLANINQWV 224

  Fly   168 ADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKPFFINEREQEMVYMMH-K 231
            .:.|..:|::.||.  :...|:|:|.||.:.:|.|.::|....|....|.::|:....|.||. :
Human   225 KEATEGKIQEFLSG--LPEDTVLLLLNAIHFQGFWRNKFDPSLTQRDSFHLDEQFTVPVEMMQAR 287

  Fly   232 TGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPNSNKISLNRVISRLNAD 296
            |...:..:.|..:.|:...|:                |:::|.::::|...:.::::|::.|:.|
Human   288 TYPLRWFLLEQPEIQVAHFPF----------------KNNMSFVVLVPTHFEWNVSQVLANLSWD 336

  Fly   297 SVKK---WFERALPQKIELSLPKFQFEQRLELTPILSLMGVNTMFTRNATFGDLTADPISLVIDD 358
            ::..   | ||  |.|:.  |||...:.:::|...||.:|:..:|......|   ....|||:..
Human   337 TLHPPLVW-ER--PTKVR--LPKLYLKHQMDLVATLSQLGLQELFQAPDLRG---ISEQSLVVSG 393

  Fly   359 AQHLAKIKVDEVGSTAAAATILLVSRSSRQPDPTKFNCNHPFVFLIYDEKVDTILFAGVYSDP 421
            .||.:.:::.|||..|||||.:.:||.|.    :.|:.|.||:|.|:::.....||.|...:|
Human   394 VQHQSTLELSEVGVEAAAATSIAMSRMSL----SSFSVNRPFLFFIFEDTTGLPLFVGSVRNP 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	serpin_crustaceans_chelicerates_insects	34..421	CDD:381059	95/386 (25%)
SERPINF2	XP_005256758.2	serpinF2_A2AP	91..454	CDD:381009	96/388 (25%)