Protein Alignment Spn88Eb and SERPINE2

DIOPT Version :9

• Sequence 1: NP_650427.1
• Gene: Spn88Eb / 41829
• FlyBaseID: FBgn0038299
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: XP_005246698.1
• Gene: SERPINE2 / 5270
• HGNCID: 8951
• Length: 410
• Species: Homo sapiens
• Alignment Length: 427
• Identity: 110/427 - (25%)
• Similarity: 194/427 - (45%)
• Gaps: 50/427 - (11%)

  Fly    12 LPVVTIAALDKPEL-SFLNEFSQIFKGERDFSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFS 75
            ||:..:|::..|.: |..|..|....|. :..:.:..||.:..|..|:..||....:.|.:....
Human    17 LPLFLLASVTLPSICSHFNPLSLEELGS-NTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLG 80

  Fly    76 SSEQTERELAQAL-----NLGWALNK-QQVLVSYTLAQRQDEFRWRQSPMELSSANRIFVDRTIN 134
            :..:|:::||..:     .:|..|.| .:.:||            :::...::.||.:||.....
Human    81 ADGRTKKQLAMVMRYGVNGVGKILKKINKAIVS------------KKNKDIVTVANAVFVKNASE 133

  Fly   135 VSNKFNT----LLYGATKELDFKNDPETGLKEINDWIADKTHNQIRDMLSSEEIT-PHTMLVLAN 194
            :...|.|    :.....:.::|: ||.:....||.|:.::|.:.|.::||.:.|. ..|.|||.|
Human   134 IEVPFVTRNKDVFQCEVRNVNFE-DPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVN 197

  Fly   195 AAYMKGQWLSQFKVEETALKPFFINEREQEMVYMMHKTGAFK---MTIDEGLQSQIIKLPYRTIY 256
            |.|.||.|.|:|:.|.|..:.|...:.:...|.|:.:...|:   .:....|....|:|||.
Human   198 AVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYH--- 259

  Fly   257 KSKETHISTPESKSDISMIIILPNSNKISLNRVISRLNADSVKKWFERALPQKIELSLPKFQFEQ 321
                        ...|||:|.||..:...|:.:|..::..::..|....:|:::::.||||....
Human   260 ------------GESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVA 312

  Fly   322 RLELTPILSLMGVNTMF-TRNATFGDLTADPISLVIDDAQHLAKIKVDEVGSTAAAA-TILLVSR 384
            :.:|...|.::|:..|| :..|.|..:|....:|.:......|||:|.|.|:.|:|| |.:|::|
Human   313 QTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIAR 377

  Fly   385 SSRQPDPTKFNCNHPFVFLIYDEKVDTILFAGVYSDP 421
            ||    |..|..:.||:|.|.......:||.|..:.|
Human   378 SS----PPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	102/396 (26%)
SERPINE2	XP_005246698.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.020