Protein Alignment Spn88Eb and SERPINB6

DIOPT Version :9

• Sequence 1: NP_650427.1
• Gene: Spn88Eb / 41829
• FlyBaseID: FBgn0038299
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: XP_011512974.1
• Gene: SERPINB6 / 5269
• HGNCID: 8950
• Length: 454
• Species: Homo sapiens
• Alignment Length: 399
• Identity: 121/399 - (30%)
• Similarity: 191/399 - (47%)
• Gaps: 51/399 - (12%)

  Fly    41 FSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGWALNK--------- 96
            |:|.|:|.:.: ..|.|:||||.|...||.:.|..:...|..::||.|    :.||
Human    89 FALNLLKTLGK-DNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQIL----SFNKSGGGGDIHQ 148

  Fly    97 --QQVLVSYTLAQRQDEFRWRQSPMELSSANRIFVDRTINVSNKFN---TLLYGA-TKELDFKND 155
              |.:|........|         ..|..|||:|.:::.:..:.|.   ...|.| .:||||.:.
Human   149 GFQSLLTEVNKTGTQ---------YLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISA 204

  Fly   156 PETGLKEINDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKPFFINE 220
            .|...|.||.|:|:||..:|.::||...:.|.|.|||.||.|.:|.|..||..|.|..:.|.:::
Human   205 VEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSK 269

  Fly   221 REQEMVYMMHKTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPNSNKIS 285
            .|::.|.||.|...||.|....:.:||:.||    |..||           ::|||:||:.. ..
Human   270 NEEKPVQMMFKQSTFKKTYIGEIFTQILVLP----YVGKE-----------LNMIIMLPDET-TD 318

  Fly   286 LNRVISRLNADSVKKW--FERALPQKIELSLPKFQFEQRLELTPILSLMGVNTMF-TRNATFGDL 347
            |..|...|..:...:|  .:....:::|:|||:|:.|:..::..:|..:|:...| ...|.|..:
Human   319 LRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGM 383

  Fly   348 TADPISLVIDDAQHLAKIKVDEVGSTAAAATILLVSRSSRQPDPTKFNCNHPFVFLIYDEKVDTI 412
            :...:||  ....|.:.::|:|.|:.|||||..::.....:..| :|..:|||:|.|...|.:.|
Human   384 SQTDLSL--SKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVP-RFCADHPFLFFIQHSKTNGI 445

  Fly   413 LFAGVYSDP 421
            ||.|.:|.|
Human   446 LFCGRFSSP 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	119/394 (30%)
SERPINB6	XP_011512974.1	PAI-2	82..454	CDD:239013	120/397 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820