Protein Alignment Spn88Eb and SERPINF1

DIOPT Version :9

• Sequence 1: NP_650427.1
• Gene: Spn88Eb / 41829
• FlyBaseID: FBgn0038299
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_001316832.1
• Gene: SERPINF1 / 5176
• HGNCID: 8824
• Length: 418
• Species: Homo sapiens
• Alignment Length: 431
• Identity: 102/431 - (23%)
• Similarity: 186/431 - (43%)
• Gaps: 68/431 - (15%)

  Fly    13 PVVTIAALDKPELSFLNEFSQIFKGERDFSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSS 77
            |..|.|.:::.:..|....:::.....:|...|.:......|:.|:..||.|...||......:.
Human    33 PDSTGALVEEEDPFFKVPVNKLAAAVSNFGYDLYRVRSSTSPTTNVLLSPLSVATALSALSLGAE 97

  Fly    78 EQTERELAQALNLGWALNK------QQVLVSYTLAQRQDEFRWRQSPMELSSANRIFVDRTINVS 136
            ::||..:.:||......:.      :::|.:.|..|:           .|.||:||..::.:.:.
Human    98 QRTESIIHRALYYDLISSPDIHGTYKELLDTVTAPQK-----------NLKSASRIVFEKKLRIK 151

  Fly   137 NKFNTLL---YGATKELDFKNDPETGLKEINDWIADKTHNQIRDML--SSEEITPHTMLVLANAA 196
            :.|...|   || |:......:|...|:|||:|:    ..|::..|  |::||.....::|...|
Human   152 SSFVAPLEKSYG-TRPRVLTGNPRLDLQEINNWV----QAQMKGKLARSTKEIPDEISILLLGVA 211

  Fly   197 YMKGQWLSQFKVEETALKPFFINEREQEMVYMMHKTGA-FKMTIDEGLQSQIIKLPYRTIYKSKE 260
            :.||||:::|...:|:|:.|:::|.....|.||....| .:..:|..|..:|.:||.
Human   212 HFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPL-------- 268

  Fly   261 THISTPESKSDISMIIILPNSNKISLNRVISRLNADSVKKWFERALPQKIE-----LSLPKFQFE 320
                    ...:|:|..||  .|::.|..   |..:|:...|...:.::::     |::||.:..
Human   269 --------TGSMSIIFFLP--LKVTQNLT---LIEESLTSEFIHDIDRELKTVQAVLTVPKLKLS 320

  Fly   321 QRLELTPILSLMGVNTMFTRNATFGDLTADPISLVIDDAQHLAKIKVDEVGSTAAAATILLVSRS 385
            ...|:|..|..|.:.::|. :..|..:|..||.|.  ..:|.|..:.:|.|:....:..|
Human   321 YEGEVTKSLQEMKLQSLFD-SPDFSKITGKPIKLT--QVEHRAGFEWNEDGAGTTPSPGL----- 377

  Fly   386 SRQPD----PTKFNCNHPFVFLIYDEKVDTILFAGVYSDPR 422
              ||.    |..::.|.||:|::.|.....:||.|...|||
Human   378 --QPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDPR 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	95/401 (24%)
SERPINF1	NP_001316832.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..39		2/5 (40%)
		PEDF	40..415	CDD:239007	96/421 (23%)
		O-glycosylated at one site	371..383		3/18 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010