Protein Alignment Spn88Eb and SERPINA10

DIOPT Version :10

• Sequence 1: NP_650427.1
• Gene: Spn88Eb / 41829
• FlyBaseID: FBgn0038299
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: XP_016876842.1
• Gene: SERPINA10 / 51156
• HGNCID: 15996
• Length: 484
• Species: Homo sapiens
• Alignment Length: 395
• Identity: 98/395 - (24%)
• Similarity: 184/395 - (46%)
• Gaps: 33/395 - (8%)

  Fly    33 QIFKGERDFSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGWALNKQ 97
            |:.|...:|..:|:::| .:...||:.||||....|:......::..||.::.:.|:| .||...
Human   114 QLAKETSNFGFSLLRKI-SMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHL-QALKPT 176

  Fly    98 QVLVSYTLAQRQDEFRWRQSPMELSSANRIFVDRTINVSNKFNTL--LYGATK--ELDFKNDPET 158
            :..:..:|.:...|...|...:.|:..:..|:.:..:|...|..|  .|..|:  .::|:|..:
Human   177 KPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQ- 240

  Fly   159 GLKEINDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKPFFINEREQ 223
            ..:.:|.:|..:|..:|..:.  :||.|.|.|:|.:....||:||:.|....|.:..|.:::.:.
Human   241 AKRLMNHYINKETRGKIPKLF--DEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKT 303

  Fly   224 EMVYMMHKTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPN--SNKISL 286
            ..|.||:..|.|..|.|:..:..::||||                :.:.:|:::|..  .:.::|
Human   304 IKVPMMYGAGKFASTFDKNFRCHVLKLPY----------------QGNATMLVVLMEKMGDHLAL 352

  Fly   287 NRVISRLNADSVKKWFERALPQKIELSLPKFQFEQRLELTPILSLMGVNTMFTRNATFGDLTADP 351
            .   ..|..|.|:.|......:.:|:..|||:.:|:.|:..:|..||:..:|:..|...:|:|..
Human   353 E---DYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATG 414

  Fly   352 ISLVIDDAQHLAKIKVDEVGSTAAAATILLVSRSSRQPDPTKFNCNHPFVFLIYDEKVDTILFAG 416
            .:|.:........|:|||.|:.|.|.   ::|..:....|.....:.||.|:||:|....:||.|
Human   415 RNLQVSRVLQRTVIEVDERGTEAVAG---ILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFLG 476

  Fly   417 VYSDP 421
            ...:|
Human   477 RVVNP 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	serpin_crustaceans_chelicerates_insects	34..421	CDD:381059	96/392 (24%)
SERPINA10	XP_016876842.1	serpinA10_PZI	107..482	CDD:381011	98/395 (25%)