DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn88Eb and serpinb1l1

DIOPT Version :9

Sequence 1:	NP_650427.1	Gene:	Spn88Eb / 41829	FlyBaseID:	FBgn0038299	Length:	426	Species:	Drosophila melanogaster
Sequence 2:	NP_001009892.2	Gene:	serpinb1l1 / 494155	ZFINID:	ZDB-GENE-040715-5	Length:	384	Species:	Danio rerio

Alignment Length:	392	Identity:	117/392 - (29%)
Similarity:	189/392 - (48%)	Gaps:	29/392 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 FSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGWALNKQQVLVSYTL 105
            |||.|.|:|.....|||:|:||.|..:||.:....:...|..::.:.|......::....:....
Zfish    11 FSLNLFKKISGGNASGNVFYSPVSISSALAMVSLGAKGNTADQMFKVLGFNSQAHQPVEQIHSNF 75

  Fly   106 AQRQDEFRWRQSPMELSSANRIFVDRTINVSNKF--NTLLY--GATKELDFKNDPETGLKEINDW 166
            .:...|....::|..||.|||::.::|..:..||  :|..|  ...:::||.|..|.....||.|
Zfish    76 KKFMSELNKPEAPYVLSLANRLYGEQTYQLIEKFLNDTKRYYDAGLEKVDFINKSEDARVNINTW 140

  Fly   167 IADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKPFFINEREQEMVYMMHK 231
            :...|..:|:|:|.|..|...|.|||.||.|.||.|..:|..|.|....|.:|:.:.:.|.|||:
Zfish   141 VEKNTQEKIKDLLPSGAIDAMTRLVLVNAIYFKGNWEEKFPKEATRDGVFRLNKNQTKPVKMMHQ 205

  Fly   232 TGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPN---SNKISLNRVISRL 293
            ...|.....|.::|.:::|||               :..::||:||||:   .....|.::...|
Zfish   206 KAEFPSGYIEEMKSHVLELPY---------------AGKNLSMLIILPDEIEDETTGLQKLERAL 255

  Fly   294 NADSVKKWFERAL--PQKIELSLPKFQFEQRLELTPILSLMGVNTMFTRNATFGDLTADPIS--L 354
            ..:.:.:|.:..:  .:::::|||||:.||..::..:|..||:..:|.....  :||....|  |
Zfish   256 TYEKLMEWTKPEVMHQREVQVSLPKFKTEQTYDMKSLLVSMGMEDVFDPQKV--NLTGMSSSNDL 318

  Fly   355 VIDDAQHLAKIKVDEVGSTAAAATILLVSRSSRQPDPTKFNCNHPFVFLIYDEKVDTILFAGVYS 419
            |:..|.|.|.::|:|.|:.|||||..:.......| |..||.:|||:|.|......:|||.|...
Zfish   319 VLSKAIHKAFVEVNEEGTEAAAATAAIEKLMCYIP-PLSFNADHPFLFFIRHNPTKSILFYGRLC 382

  Fly   420 DP 421
            .|
Zfish   383 SP 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	116/387 (30%)
serpinb1l1	NP_001009892.2	PAI-2	4..384	CDD:239013	116/390 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820