Protein Alignment Spn88Eb and SERPINC1

DIOPT Version :10

• Sequence 1: NP_650427.1
• Gene: Spn88Eb / 41829
• FlyBaseID: FBgn0038299
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_001373231.1
• Gene: SERPINC1 / 462
• HGNCID: 775
• Length: 505
• Species: Homo sapiens
• Alignment Length: 414
• Identity: 107/414 - (25%)
• Similarity: 186/414 - (44%)
• Gaps: 67/414 - (16%)

  Fly    57 NLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGWALNKQQVLVSYTLAQRQDE-FRWRQSPME 120
            |:|.||.|...|..:....:...|.::|.:.........|....:.:..|:.... :|......:
Human   107 NIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSK 171

  Fly   121 LSSANRIFVDRTINVSNKF---NTLLYGA-TKELDFKNDPETGLKEINDWIADKTHNQIRDMLSS 181
            |.||||:|.|:::..:..:   :.|:||| .:.||||.:.|.....||.|:::||..:|.|::.|
Human   172 LVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPS 236

  Fly   182 EEITPHTMLVLANAAYMK-----------------------------------------GQWLSQ 205
            |.|...|:|||.|..|.|                                         |.|.|:
Human   237 EAINELTVLVLVNTIYFKVLRMALERPQGLPLALQLTPFFFKWRDRSPERANGLPKATQGLWKSK 301

  Fly   206 FKVEETALKPFFINEREQEMVYMMHKTGAFK-MTIDEGLQSQIIKLPYRTIYKSKETHISTPESK 269
            |..|.|..:.|:..:.|.....||::.|.|: ..:.||  :|:::||::               .
Human   302 FSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAEG--TQVLELPFK---------------G 349

  Fly   270 SDISMIIILPNSNKISLNRVISRLNADSVKKWFERALPQKIELSLPKFQFEQRLELTPILSLMGV 334
            .||:|::|||...| ||.:|...|..:.:::|.:......:.:.:|:|:.|....|...|..||:
Human   350 DDITMVLILPKPEK-SLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGL 413

  Fly   335 NTMFT--RNATFGDLTADPISLVIDDAQHLAKIKVDEVGSTAAAATILLVSRSSRQPDPTKFNCN 397
            ..:|:  ::...|.:......|.:.||.|.|.::|:|.||.|||:|.::::..|..|:...|..|
Human   414 VDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKAN 478

  Fly   398 HPFVFLIYDEKVDTILFAGVYSDP 421
            .||:..|.:..::||:|.|..::|
Human   479 RPFLVFIREVPLNTIIFMGRVANP 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	serpin_crustaceans_chelicerates_insects	34..421	CDD:381059	106/412 (26%)
SERPINC1	NP_001373231.1	serpinC1_AT3	70..504	CDD:381002	107/414 (26%)