DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn88Eb and serpine2

DIOPT Version :9

Sequence 1:	NP_650427.1	Gene:	Spn88Eb / 41829	FlyBaseID:	FBgn0038299	Length:	426	Species:	Drosophila melanogaster
Sequence 2:	NP_956478.1	Gene:	serpine2 / 393153	ZFINID:	ZDB-GENE-040426-848	Length:	395	Species:	Danio rerio

Alignment Length:	397	Identity:	104/397 - (26%)
Similarity:	187/397 - (47%)	Gaps:	48/397 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 DFSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGWALNKQQVLVSYT 104
            |..|.:..|:.:.....|:..||....:.|.:....:...|.|:|...|       |.:....|.
Zfish    32 DLGLQVFMQVLQDRAQENVLLSPHGVASVLGMLLPGAHGDTRRQLLNGL-------KYKKNGPYK 89

  Fly   105 LAQRQDEFRWRQSPMEL-SSANRIFVDRTINVSNKFNTLLYGATKE--------LDFKNDPETGL 160
            :.::..:....:|..:: :.||.:|.:...::...|    ..|.:|        :|: :|||...
Zfish    90 MLRKLHKSLTTKSNADIVTIANALFPNEGFSMKEDF----LSANRENFLCESHSVDY-SDPEAAA 149

  Fly   161 KEINDWIADKTHNQIRDMLSSEEI-TPHTMLVLANAAYMKGQWLSQFKVEETALKPFFINEREQE 224
            :.||||:.:.|..||..:::::.. |..|.||..|:.:.||.|.|:|:.:.|..:.|...:....
Zfish   150 QSINDWVKNSTKGQIPSVVTADMFDTALTRLVAVNSIFFKGLWKSRFQPQSTKPRSFTAGDGNTY 214

  Fly   225 MVYMMHKTGAFKM---TIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPNSNKISL 286
            .|.||.:...|.|   :..:|.:..:|:|||.               .:.:||.|.||..:...|
Zfish   215 KVPMMSQLSVFNMGQASTPDGQKYIVIELPYH---------------GNSMSMFIALPTEDSTPL 264

  Fly   287 NRVISRLNADSVKKWFERALPQKIELSLPKFQFEQRLELTPILSLMGVNTMFTRN-ATFGDLTAD 350
            :.::..::.::::.|.:...|:::.|.:|||..||.|:|...|..:|:..:|.:| |.|..|:::
Zfish   265 SSILPHISTNTIQSWTKLMNPRRMRLLMPKFTVEQELDLETPLKALGIKDIFDQNKADFRHLSSE 329

  Fly   351 PISLVIDDAQHLAKIKVDEVGSTAAAAT-ILLVSRSSRQPDPTKFNCNHPFVFLIYDEKVDTILF 414
              |:.:..|...|||:|:|.|:.|:|.| ::|.:|||    |.....:.||:|||......||||
Zfish   330 --SIYVSKALQKAKIEVNEDGTKASATTSVILHARSS----PPWVTVDRPFLFLIRHNSSGTILF 388

  Fly   415 AGVYSDP 421
            ||..:.|
Zfish   389 AGQINKP 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	103/392 (26%)
serpine2	NP_956478.1	PAI-1_nexin-1	26..395	CDD:239006	103/395 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.020