Protein Alignment Spn88Eb and SERPINA2

DIOPT Version :9

• Sequence 1: NP_650427.1
• Gene: Spn88Eb / 41829
• FlyBaseID: FBgn0038299
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_006211.2
• Gene: SERPINA2 / 390502
• HGNCID: 8985
• Length: 421
• Species: Homo sapiens
• Alignment Length: 401
• Identity: 83/401 - (20%)
• Similarity: 177/401 - (44%)
• Gaps: 56/401 - (13%)

  Fly    40 DFSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGWALNK-------- 96
            |.:..|.|::.::..:.|:..:|.|...|..:....:...|..|:.:.||:......
Human    59 DLAFDLYKELADLSQTSNVLVTPTSVAMAFAMLSLGTKADTRTEILEGLNVNLTETPEAKIHECF 123

  Fly    97 QQVLVSYTLAQRQDEFRWRQSPMELSSANRIFVDRTINVSNKF----NTLLYGATKELDFKNDPE 157
            ||||.:.:   |.|      :.::|::.:.:||::::.:.:.|    ..|.:.....::|: |.|
Human   124 QQVLQALS---RPD------TRLQLTTGSSLFVNKSMKLVDTFLEDTKKLYHSEASSINFR-DTE 178

  Fly   158 TGLKEINDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKPFFINERE 222
            ...::||:::..:|..::.|::  :.:...|.|.|.:.....|:|..:||.|...::.|.::::.
Human   179 EAKEQINNYVEKRTGRKVVDLV--KHLKKDTSLALVDYISFHGKWKDKFKAEHIMVEGFHVDDKT 241

  Fly   223 QEMVYMMHKTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPNSNKI-SL 286
            ...|.|::..|.|.:..|..|.|.::...|                ..:.:...|||:..|: .|
Human   242 IIRVPMINHLGRFDIHRDRELSSWVLAQHY----------------VGNATAFFILPDPKKMWQL 290

  Fly   287 NRVISRLNADSVKKWFERALPQKIELSLPKFQFEQRLELTPILSLMGVNTMFTRNATFGDLTAD- 350
            ...::..:.:::::.|:   .:.|.|..||.......:|..:|..:|:..:|:..|....::.:
Human   291 EEKLTYSHLENIQRAFD---IRSINLHFPKLSISGTYKLKRVLRNLGITKIFSNEADLSGVSQEA 352

  Fly   351 PISLVIDDAQHLAKIKVDEVGSTAAAATILLVSRSSRQPDPTKFNC---NHPFVFLIYDEKVDTI 412
            |:.|  ..|.|:|.:.:||.|:.|..|..|      .:...:|:..   |.||:.:|.|:..:..
Human   353 PLKL--SKAVHVAVLTIDEKGTEATGAPHL------EEKAWSKYQTVMFNRPFLVIIKDDITNFP 409

  Fly   413 LFAGVYSDPRQ 423
            ||.|...:|.|
Human   410 LFIGKVVNPTQ 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	81/394 (21%)
SERPINA2	NP_006211.2	SERPIN	62..418	CDD:214513	80/394 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010