DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn88Eb and Spn28Dc

DIOPT Version :9

Sequence 1:	NP_650427.1	Gene:	Spn88Eb / 41829	FlyBaseID:	FBgn0038299	Length:	426	Species:	Drosophila melanogaster
Sequence 2:	NP_609172.1	Gene:	Spn28Dc / 34091	FlyBaseID:	FBgn0031973	Length:	536	Species:	Drosophila melanogaster

Alignment Length:	471	Identity:	117/471 - (24%)
Similarity:	193/471 - (40%)	Gaps:	102/471 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 VTIAALDKPELSFLNEFSQIFKGERDFSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQ 79
            |.:|..|:...|.|| |:.|. |:.     |.....:||       ||.|..::|.|....:..:
  Fly   100 VDLATSDRIANSVLN-FANIL-GQH-----LANGKTQIY-------SPLSIVHSLALLLLGAKGR 150

  Fly    80 TERELAQALNL--GWALNKQQVLVSYTLAQRQDE--------FRWRQSPM-------------EL 121
            :..||:...::  ...|::|..|:...|.|...|        ..||.|..             |:
  Fly   151 SYEELSTVFDIPDTSRLHEQFGLMLQDLQQPTREAISAGRPLTDWRASSAMRSNRRAQRPGAHEV 215

  Fly   122 SSANRIFVDRTINVSNKFNTLL---YGATKEL-DFKNDPETGLKEINDWIADKTHNQIRDMLSSE 182
            ..||.:|......::..:..::   |.:..:: ||:..|.|....||.::|..|.|.|.::::|
  Fly   216 HLANGLFTQTGYTLNPDYRRVIVEVYASDLQIQDFEGSPATARYNINAYVAQHTKNHIENIIAS- 279

  Fly   183 EITPHTMLVLANAAYMKGQWLSQFKVEETALKP--FFINEREQE---MVYMMHKTGAFKMTIDEG 242
            :|...|.::||||.|.|..|.:.|  .|:|.:|  |:.|....|   .|.||...||:....|..
  Fly   280 DIPQTTRMILANALYFKAFWETDF--IESATRPDNFYPNGEGTEPVMRVQMMATGGAYPYHEDHE 342

  Fly   243 LQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPNSNKI-SLNRVISRLNADSVKKWFERAL 306
            |..:||.||||       .::||        |.||.|..:.: .|..:..||.||.::....|..
  Fly   343 LGCKIIGLPYR-------GNLST--------MYIIQPFKSSVRELMALQKRLTADKIESMISRMY 392

  Fly   307 PQKIELSLPKFQFEQRLELTPILSLMGVNTMFT-------------------------------R 340
            .:...::.||....:.:.|..::..||:..:|:                               |
  Fly   393 RRAALVAFPKMHLTESVNLKTVMQRMGLGGIFSAVQNDLSLIATNEATRTNALGGNSLQNLEAQR 457

  Fly   341 NATFGDLTADPISLVIDDAQHLAKIKVDEVGSTAAAATILLVSRSSRQPDPTKFNCNHPFVFLIY 405
            .|..|...:|   ||:||..|.....|:|.|:.|||:::..:.:|.  || ..|..:.||:.|:.
  Fly   458 RAGTGGARSD---LVVDDIVHKVDFTVNEQGTEAAASSVTYLKKSG--PD-VLFRGDTPFMVLVR 516

  Fly   406 DEKVDTILFAGVYSDP 421
            .:....:||.|:.::|
  Fly   517 HDPTKLVLFYGLINEP 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	108/444 (24%)
Spn28Dc	NP_609172.1	SERPIN	111..527	CDD:238101	112/453 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010