DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn88Eb and Serpinb1b

DIOPT Version :9

Sequence 1:	NP_650427.1	Gene:	Spn88Eb / 41829	FlyBaseID:	FBgn0038299	Length:	426	Species:	Drosophila melanogaster
Sequence 2:	XP_038952280.1	Gene:	Serpinb1b / 306891	RGDID:	1560658	Length:	380	Species:	Rattus norvegicus

Alignment Length:	409	Identity:	109/409 - (26%)
Similarity:	189/409 - (46%)	Gaps:	67/409 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 FSLALMKQIREIYPSGNLFFSPFSTYNALLLAYF---SSSEQTERELAQALNLG---------WA 93
            |:|.|...:.|..|:||: |||||..:||.:.:.   .||..:...||:..:..         .:
  Rat    11 FALELFHTLSESSPTGNI-FSPFSISSALAMVFLGAKGSSAPSSLRLAETFHFDSVEDIHSRFQS 74

  Fly    94 LNKQQVLVSYTLAQRQDEFRWRQSPMELSSANRIFVDRTINVSNKF---NTLLYGA-TKELDFKN 154
            ||.              |.|...:...|..|||::.::|.|...:|   ...:||| ...:||::
  Rat    75 LNA--------------EMRKHGASHTLKVANRLYGEKTYNFLPEFLASTQKMYGADLAPVDFQH 125

  Fly   155 DPETGLKEINDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKPFFIN 219
            ..|...||||.|:..:|..:|.::|:...:...|.|||.||.|.||.|..:|....|...||.:|
  Rat   126 ASEDARKEINKWVKGQTEGKIPELLAGGVVNSTTKLVLVNAIYFKGIWQEKFLTRHTTDAPFRLN 190

  Fly   220 EREQEMVYMMHKTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILP---NS 281
            :::.:||.||::...|.......|:.:::::||:               ..::||:|:||   ..
  Rat   191 KKDTKMVKMMYQKEKFPFGYIPDLKCKVLEMPYQ---------------GGELSMVILLPEDIED 240

  Fly   282 NKISLNRVISRLNADSVKKWFERALPQKIE--LSLPKFQFEQRLELTPILSLMGVNTMFTRNATF 344
            ....|.::..:|..:.:.:|.:....::|:  ::||||:.|:...|...|..:|:..:|  :::.
  Rat   241 ESTGLQKIEEQLTLEKLYEWTKHENLKEIDVHVNLPKFKIEESYILNSNLGRLGLQDLF--SSSK 303

  Fly   345 GDLT--ADPISLVIDDAQHLAKIKVDEVGSTAAAAT-----ILLVSRSSRQPDPTKFNCNHPFVF 402
            .||:  ::...:.|....|.:.::|:|.|:.|||||     ..|||..:       |..:|||:|
  Rat   304 ADLSGMSESRDIFISKIVHKSFVEVNEEGTEAAAATAGLVEYCLVSIEA-------FIVDHPFLF 361

  Fly   403 LIYDEKVDTILFAGVYSDP 421
            .|.......:||.|....|
  Rat   362 FIRHNPTANMLFFGRVCSP 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	108/404 (27%)
Serpinb1b	XP_038952280.1	serpinB1_LEI	1..380	CDD:381028	108/407 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020