DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn88Eb and RGD1564786

DIOPT Version :9

Sequence 1:	NP_650427.1	Gene:	Spn88Eb / 41829	FlyBaseID:	FBgn0038299	Length:	426	Species:	Drosophila melanogaster
Sequence 2:	XP_006253935.2	Gene:	RGD1564786 / 306889	RGDID:	1564786	Length:	420	Species:	Rattus norvegicus

Alignment Length:	436	Identity:	115/436 - (26%)
Similarity:	200/436 - (45%)	Gaps:	54/436 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 HTFSLVLLALLPVVTIAALDKPELSFLNEFSQIFKGERDFSLALMKQIREIYPSGNLFFSPFSTY 66
            :||..|.:..:.::.         |.|.....:.|...:|::.|.|.:.|.. |.|:|||..|..
  Rat    23 YTFDCVFMMFIVILH---------SRLTIMDPLLKANGNFAIKLFKVLGEDI-SKNVFFSLPSIS 77

  Fly    67 NALLLAYFSSSEQTERELAQALNL------GWALNKQQVLVSYTLAQRQDEFRWRQSPMELSSAN 125
            :||.:....::..|..::.||::|      |.....|..|...|...:.|      :...|..||
  Rat    78 SALSMILMGANGTTASQICQAMSLDKCNSIGGGDVHQHFLSLLTKVNKTD------TRCMLRKAN 136

  Fly   126 RIFVDRTINVSNKFNTL---LYGA-TKELDFKNDPETGLKEINDWIADKTHNQIRDMLSSEEITP 186
            .:|::.:..:...|...   ||.| .:|||||..||...:.||.|:|.||.:.||::|....:..
  Rat   137 SVFIEDSFEILASFKDACHKLYEAEIEELDFKGAPEQSRQHINTWVAKKTEDIIRELLPPCTVNS 201

  Fly   187 HTMLVLANAAYMKGQWLSQFKVEETALKPFFINEREQEMVYMMHKTGAFKMTIDEGLQSQIIKLP 251
            :|.|.|.|..|.||.....|...:|...||.::..|::.|.||.:...||||..:.:.:|::.||
  Rat   202 NTCLFLVNVIYFKGSLEKPFNKADTREMPFKVSMNEKKTVQMMSQKSTFKMTYVKDISTQVLTLP 266

  Fly   252 YRTIYKSKETHISTPESKSDISMIIILPNSNKISLNRVISRLNADSVKKWF-ERALPQK-IELSL 314
            :               ..|.:||...:|:|: ::..::.:.|..|...:|. |..:.:| :|:.|
  Rat   267 F---------------ENSILSMYFFVPDSH-VAQRKLENELTYDKFLEWTDEDTMEEKEMEVFL 315

  Fly   315 PKFQFEQRLELTPILSLMGVNTMFTRN-ATFGDLTADPISLVIDDAQHLAKIKVDEVGSTAAAAT 378
            |:.:.|:..::..:|..:|:...|..: |.|..:::.. .|.:....|.:.:::.|.|:.|||.|
  Rat   316 PRIKLEESYDMNGVLRKLGMTDAFEEDKADFSGISSKH-GLFLSKVVHKSFVEMSEEGTEAAAPT 379

  Fly   379 ILLVSRSSRQPDPTKFNC---NHPFVFLIYDEKVDTILFAGVYSDP 421
            .::..:|...|     .|   :|||:|.|.|.:...|||.|.:|.|
  Rat   380 DVVTMKSPLTP-----RCLIADHPFLFSIQDTRSKEILFLGRFSSP 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	107/396 (27%)
RGD1564786	XP_006253935.2	SERPIN	46..420	CDD:294093	109/402 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010