DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn88Eb and Serpinc1

DIOPT Version :9

Sequence 1:	NP_650427.1	Gene:	Spn88Eb / 41829	FlyBaseID:	FBgn0038299	Length:	426	Species:	Drosophila melanogaster
Sequence 2:	NP_001012027.1	Gene:	Serpinc1 / 304917	RGDID:	1307404	Length:	465	Species:	Rattus norvegicus

Alignment Length:	429	Identity:	120/429 - (27%)
Similarity:	201/429 - (46%)	Gaps:	48/429 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VLLALLPVVT---IAALDKPELSFLNEFSQIF---KGERDFSLALMKQIREIYPSGNLFFSPFST 65
            ||...:|..|   :..|.|....|...|.|..   |.:.|                |:|.||.|.
  Rat    68 VLEQKVPEATNRRVWELSKANSRFATNFYQHLADSKNDND----------------NIFLSPLSI 116

  Fly    66 YNALLLAYFSSSEQTERELAQALNLGWALNKQQVLVSYTLAQRQDE-FRWRQSPMELSSANRIFV 129
            ..|..:....:...|.::|.:.........|....:.:..|:.... :|.......|.||||:|.
  Rat   117 STAFAMTKLGACNNTLKQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSNLVSANRLFG 181

  Fly   130 DRTINVSNKF---NTLLYGA-TKELDFKNDPETGLKEINDWIADKTHNQIRDMLSSEEITPHTML 190
            |:::..:..:   :.::||| .:.||||.:||.....||:|:|:||..:|:|::....|...|.|
  Rat   182 DKSLTFNESYQDVSEIVYGAKLQPLDFKENPEQSRVTINNWVANKTEGRIKDVIPQGAIDELTAL 246

  Fly   191 VLANAAYMKGQWLSQFKVEETALKPFFINEREQEMVYMMHKTGAFK-MTIDEGLQSQIIKLPYRT 254
            ||.|..|.||.|.|:|..|.|..:||...:.:..:|.||::.|.|| ..:.||  :|::::|::
  Rat   247 VLVNTIYFKGLWKSKFSPENTRKEPFHKVDGQSCLVPMMYQEGKFKYRRVGEG--TQVLEMPFK- 308

  Fly   255 IYKSKETHISTPESKSDISMIIILPNSNKISLNRVISRLNADSVKKWFERALPQKIELSLPKFQF 319
                          ..||:|::|||...| ||.:|...|..:.:::|.:......:.:.:|:|:.
  Rat   309 --------------GDDITMVLILPKPEK-SLAKVEQELTPELLQEWLDELSEVMLVVHVPRFRI 358

  Fly   320 EQRLELTPILSLMGVNTMFT--RNATFGDLTADPISLVIDDAQHLAKIKVDEVGSTAAAATILLV 382
            |....|...|..||:..:|:  ::...|.:......|.:.||.|.|.::|:|.||.|||:|.:::
  Rat   359 EDSFSLKEQLQDMGLVDLFSPEKSQLPGIIAEGRDDLFVSDAFHKAFLEVNEEGSEAAASTSVVI 423

  Fly   383 SRSSRQPDPTKFNCNHPFVFLIYDEKVDTILFAGVYSDP 421
            :..|..|....|..|.||:.||.:..::||:|.|..|:|
  Rat   424 TGRSLNPSRVTFKANRPFLVLIREVALNTIIFMGRVSNP 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	108/388 (28%)
Serpinc1	NP_001012027.1	antithrombin-III_like	80..459	CDD:239000	114/412 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020