DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn88Eb and Serpinb11

DIOPT Version :10

Sequence 1:NP_650427.1 Gene:Spn88Eb / 41829 FlyBaseID:FBgn0038299 Length:426 Species:Drosophila melanogaster
Sequence 2:XP_006249694.3 Gene:Serpinb11 / 304689 RGDID:1306497 Length:463 Species:Rattus norvegicus


Alignment Length:414 Identity:123/414 - (29%)
Similarity:203/414 - (49%) Gaps:41/414 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 FLNEFSQIFKGERDFSLALMKQIREIYPSGNLFFSPFSTYNA----LLLAYFSSSEQTERELAQA 87
            |......|.....:|.|.:.|::.......|:||||.:|:.|    ||.|...|:||.|:.|...
  Rat    72 FGRRMDSITTANTEFCLDVFKELSSSNVGENIFFSPLTTFYALSMLLLGARGKSAEQMEKVLHYD 136

  Fly    88 LNLGWALNKQQVLVSYTLAQ---RQDEFRWRQSPM----ELSSANRIFVDRTINVSNKF----NT 141
            ...|:.  |.::..|...:|   ...|||...|.:    .||.||||:..:.|....::    ..
  Rat   137 NFSGFL--KAKIKNSSECSQGGRMHPEFRALVSHINQQNSLSIANRIYGTKAIEFHKQYIRCCEK 199

  Fly   142 LLYGATKELDFKNDPETGLKEINDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQF 206
            |.....:.:||:...|...|.||.|:.:|||.:|.::.....|.|.:::||.:|.|.||||.::|
  Rat   200 LYQAKLQTVDFELSAEETRKSINAWVENKTHGKITNLFDKGTIDPSSVMVLVSAIYFKGQWQNKF 264

  Fly   207 KVEETALKPFFINEREQEMVYMMHKTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSD 271
            :..||...||.|:..:..:|.||::||.||:...:..|.|:::|||               :.:.
  Rat   265 QKTETVKAPFHISVGKSAVVDMMYQTGTFKLAFIKEPQMQVLELPY---------------ANNK 314

  Fly   272 ISMIIILPNSNKISLNRVISRLNADSVKKWF--ERALPQKIELSLPKFQFEQRLELTPILSLMGV 334
            :.|||:|| ....|:|::...|||..:::|.  ...:.:.:::.:|||....:.:|..:|..:|:
  Rat   315 LRMIILLP-VGTASVNQIEKHLNAKMLREWTSPSNMVERVVDVHIPKFSLSVKYDLNTLLKSLGM 378

  Fly   335 NTMFTRNATFGDLT--ADPISLVIDDAQHLAKIKVDEVGSTAAAATILLVSRSSRQPDPTKFNCN 397
            :.:|  |....||:  :....|.:....|.:.:.|:|.|:.|||||...:| ..|.|...:|..|
  Rat   379 SDIF--NVAKADLSGMSPDKGLYLSKVVHKSYVDVNEEGTEAAAATGETIS-VKRLPVTVQFTAN 440

  Fly   398 HPFVFLIYDEKVDTILFAGVYSDP 421
            .||:|.|:||..: |||||.::.|
  Rat   441 CPFLFFIWDEFYN-ILFAGKFASP 463

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn88EbNP_650427.1 serpin_crustaceans_chelicerates_insects 34..421 CDD:381059 121/405 (30%)
Serpinb11XP_006249694.3 None

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