DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn88Eb and Serpinb6e

DIOPT Version :9

Sequence 1:	NP_650427.1	Gene:	Spn88Eb / 41829	FlyBaseID:	FBgn0038299	Length:	426	Species:	Drosophila melanogaster
Sequence 2:	XP_006253937.2	Gene:	Serpinb6e / 291087	RGDID:	1561697	Length:	379	Species:	Rattus norvegicus

Alignment Length:	407	Identity:	108/407 - (26%)
Similarity:	198/407 - (48%)	Gaps:	51/407 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 IFKGERDFSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNL-------G 91
            :.:....|:|.:::.:.| ..|.|:||||.|.:::|.:....::..|..::::.|:|       |
  Rat     4 LLEANATFALKVLRVLGE-DSSKNVFFSPLSMFSSLSMILLGANGTTASQISKVLSLYNCNGNGG 67

  Fly    92 WALNK--QQVLVSYTLAQRQDEFRWRQSPMELSSANRIFVDRTINVSNKFN---TLLYGATKE-L 150
            ...::  |.:|.....:.|:.         .|.::|.:||:.:..:...|.   ...|.|..| :
  Rat    68 GDFHQCFQSLLTEVNKSDRRH---------MLKTSNSVFVEDSFEILASFKDSCRKFYEAEIENM 123

  Fly   151 DFKNDPETGLKEINDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKP 215
            |||..||...:.||.|:|.||.:.||::||...:..:|.|||.|:.|.||.|...|..|:|...|
  Rat   124 DFKGAPEQSRQHINTWVAKKTEDVIRELLSPGTVNSNTQLVLMNSFYFKGNWEKPFNKEDTREMP 188

  Fly   216 FFINEREQEMVYMMHKTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPN 280
            |.:::.|:::|.||.....|:....|.:.:.:..|||               ..:.:|:.|:||:
  Rat   189 FKVSKNEKKIVQMMFNKSNFRTYHVEDISTTLALLPY---------------LGNQLSITIMLPD 238

  Fly   281 SNKISLNRVISRLNADSVKKW--FERALPQKIELSLPKFQFEQRLELTPILSLMGVNTMF-TRNA 342
             ..:.|..|.:::..:.:.:|  .|....:::|:.||:|:.|:..::..:|..:|:...| ...|
  Rat   239 -EYVELRTVENQITYEKLIEWTRLENMQEEEVEILLPRFKLEESYDMKNVLCKLGMTNAFEDGRA 302

  Fly   343 TFGDLTADPISLVIDDAQHLAKIKVDEVGSTAAAATILLVSRSSRQPDPTKFNC---NHPFVFLI 404
            .|..:::.| .|.:....|.:.::|:|.|:.|||.|.::...|...|     .|   :|||:|||
  Rat   303 DFSGISSKP-GLFLSKVVHKSVVEVNEEGTEAAAPTEIVTMGSPLSP-----QCLVADHPFLFLI 361

  Fly   405 YDEKVDTILFAGVYSDP 421
            .|::...|||.|.:|.|
  Rat   362 QDDRNKAILFLGRFSSP 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	106/399 (27%)
Serpinb6e	XP_006253937.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010