DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn88Eb and Serpinb6a

DIOPT Version :9

Sequence 1:	NP_650427.1	Gene:	Spn88Eb / 41829	FlyBaseID:	FBgn0038299	Length:	426	Species:	Drosophila melanogaster
Sequence 2:	XP_006253933.1	Gene:	Serpinb6a / 291085	RGDID:	735108	Length:	400	Species:	Rattus norvegicus

Alignment Length:	402	Identity:	121/402 - (30%)
Similarity:	198/402 - (49%)	Gaps:	44/402 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 KGERDFSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNL-------GWA 93
            :|...|:|.|:|.:.| ..|.|:|.||.|...||.:.:..:...|..::.|.|:|       |..
  Rat    27 EGNGIFALKLLKTLSE-DSSNNIFLSPISISAALTMVFMGAKGMTASQMVQTLSLDKCSGNGGGD 90

  Fly    94 LNK--QQVLVSYTLAQRQDEFRWRQSPMELSSANRIFVDRTINVSNKFNTL---LYGA-TKELDF 152
            :::  |.:|........|         ..|.:|||:|.::|.::...|...   .|.| .:||||
  Rat    91 VHQGFQSLLAEVNKTGTQ---------YLLKTANRLFGEKTCDILASFKDACRKFYEAEMEELDF 146

  Fly   153 KNDPETGLKEINDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKPFF 217
            |.|.|...:.||.|:|.||.::|:::|:...:.|.|:|||.||.|.||.|..||..|.|..|||.
  Rat   147 KGDTEQSRQRINTWVAKKTEDKIKELLAPGIVDPDTVLVLVNAIYFKGNWDKQFNKEHTREKPFK 211

  Fly   218 INEREQEMVYMMHKTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPNSN 282
            :::.|::.|.||.....||||....:.::|:.|||               :.::::|||:||:.:
  Rat   212 VSKTEEKPVQMMFMKSTFKMTYIGEIFTKILLLPY---------------AGNELNMIIMLPDEH 261

  Fly   283 KISLNRVISRLNADSVKKW--FERALPQKIELSLPKFQFEQRLELTPILSLMGVNTMFTR-NATF 344
             |.|..|...|..:...:|  .:....:::|:.||:|:.|:..::..:|..:|:...|.. .|.|
  Rat   262 -IELKTVEKELTYEKFIEWTRLDMLDEEEVEVFLPRFKLEENYDMKVVLGKLGMTDAFMEGRADF 325

  Fly   345 GDLTADPISLVIDDAQHLAKIKVDEVGSTAAAATILLVSRSSRQPDPTKFNCNHPFVFLIYDEKV 409
            ..: |....|.:....|.|.::|:|.|:.|.|||...::....:..| :|..:|||:|.|...|.
  Rat   326 SGI-ASKQGLFLSKVIHKAFVEVNEEGTEAVAATGSTITMRCLRFTP-RFLADHPFLFFIQHVKT 388

  Fly   410 DTILFAGVYSDP 421
            ..|||.|.:|.|
  Rat   389 KGILFCGRFSSP 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	119/396 (30%)
Serpinb6a	XP_006253933.1	SERPIN	25..400	CDD:294093	120/400 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820