DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn88Eb and Serpinb8

DIOPT Version :9

Sequence 1:	NP_650427.1	Gene:	Spn88Eb / 41829	FlyBaseID:	FBgn0038299	Length:	426	Species:	Drosophila melanogaster
Sequence 2:	NP_001099418.1	Gene:	Serpinb8 / 288937	RGDID:	1309833	Length:	375	Species:	Rattus norvegicus

Alignment Length:	394	Identity:	115/394 - (29%)
Similarity:	194/394 - (49%)	Gaps:	42/394 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 FSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNL---GWALNKQQVLVS 102
            |:::|:|.:.|...|.||||.|.|..:||.:.|..:...|..:::|.|.|   |......|.|::
  Rat    11 FAISLLKILGEEDKSRNLFFCPMSVSSALAMVYLGAKGNTATQMSQVLGLSGDGDVHQGFQTLLA 75

  Fly   103 YTLAQRQDEFRWRQSPMELSSANRIFVDRTINVSNKF----NTLLYGATKELDFKNDPETGLKEI 163
                    |.....:...|.||.|:|.:.:.:..:.|    ........:|:.|..|.|...|.|
  Rat    76 --------EVNKSGTQYLLKSACRLFGEESCDFLSTFKESCQKFYQAGIEEMSFVKDTEGCRKRI 132

  Fly   164 NDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKPFFINEREQEMVYM 228
            |||:.:||..:|.::||...:.|.|.|||.||.|.||:|.:||..:.|...||..|:.|::.|.|
  Rat   133 NDWVLEKTEGKISEVLSPGTVCPLTKLVLVNAMYFKGKWKAQFDRKYTRGMPFKTNQEEKKTVQM 197

  Fly   229 MHKTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPNSNKISLNRVISRL 293
            |.|...|||...:.:.:|::.|||               ::.::||:::||:.:. .|..|...|
  Rat   198 MFKHAKFKMAHVDEVNAQVLALPY---------------AEDELSMVVLLPDESS-DLTVVEKAL 246

  Fly   294 NADSVKKWF--ERALPQKIELSLPKFQFEQRLELTPILSLMGVNTMFTR-NATFGDLTAD---PI 352
            ..:.::.|.  |.....|:::..|:.:.|:..:|..:|..:|:...|.. .|.|..:|:.   |:
  Rat   247 TYEKLRAWTNPETLTESKVQVFFPRLKLEESYDLETVLQSLGMTDAFEETKADFSGMTSKKNVPV 311

  Fly   353 SLVIDDAQHLAKIKVDEVGSTAAAATILLVSRSSRQPDPTKFNCNHPFVFLIYDEKVDTILFAGV 417
            |.|    .|...::|:|.|:.|||.|.::.:..|.:.:| :|..:.||:|.|:.:|..:|||.|.
  Rat   312 SKV----AHKCFVEVNEEGTEAAATTAVIRNTRSCRIEP-RFCADRPFLFFIWHQKTSSILFCGR 371

  Fly   418 YSDP 421
            :|.|
  Rat   372 FSSP 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	113/389 (29%)
Serpinb8	NP_001099418.1	SERPIN	4..375	CDD:294093	114/392 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920