DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn88Eb and Serpinf2

DIOPT Version :9

Sequence 1:	NP_650427.1	Gene:	Spn88Eb / 41829	FlyBaseID:	FBgn0038299	Length:	426	Species:	Drosophila melanogaster
Sequence 2:	NP_001011892.1	Gene:	Serpinf2 / 287527	RGDID:	1306692	Length:	491	Species:	Rattus norvegicus

Alignment Length:	387	Identity:	104/387 - (26%)
Similarity:	176/387 - (45%)	Gaps:	45/387 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 FSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQAL--NLGWALNKQQVLVSY 103
            |:..|...:.:...|.||..||.|...||......:..||...|.:.|  |:|..:..   |:|:
  Rat    89 FTTDLFSLVAQTSTSSNLVLSPLSVALALSHLALGARNQTLENLQRVLHMNMGSCIPH---LLSH 150

  Fly   104 TLAQRQDEFRWRQSPMELSSANRIFVDRTINVSNKF---NTLLYGATKELDFKNDPETGLKEIND 165
                    |....:|..:..|.||::.:...:.:.|   :..|:|| |.:......|..|..||.
  Rat   151 --------FCQNLNPGTIRLAARIYLQKGFPIKDDFLEQSEKLFGA-KPVKLTGRQEEDLMNINK 206

  Fly   166 WIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKPFFINEREQEMVYMMH 230
            |:.:.|..:|.|.||  |:..:|:|:|.||.:..|.|.::|....|....|.::|:....|.|||
  Rat   207 WVKEATEGKIEDFLS--ELPDNTVLLLLNAIHFHGFWRTKFDPSLTQKDSFHLDEQFTVPVAMMH 269

  Fly   231 -KTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPNSNKISLNRVISRLN 294
             ::...:..:.|..:.|:...|:                ::::|.::|:|.....:::.|::.|.
  Rat   270 AQSYPLRWFLLEQPEIQVAHFPF----------------QNNMSFVVIMPTYFGWNVSEVLANLT 318

  Fly   295 ADSVKKWFERALPQKIELSLPKFQFEQRLELTPILSLMGVNTMFTRNATFGDLTADPISLVIDDA 359
            .|::.:...|..|.|:.  |||...||.|:|...||.:|:..:|......|  .:|. |||:...
  Rat   319 WDTLYQPSMREKPTKVR--LPKLHLEQHLDLVATLSKLGLQDLFQSPDLRG--ISDQ-SLVVSSV 378

  Fly   360 QHLAKIKVDEVGSTAAAATILLVSRSSRQPDPTKFNCNHPFVFLIYDEKVDTILFAGVYSDP 421
            ||.:.:::.|.|..|||||...::|.|.    :.|..|.||:|.|.:|.:...||.|...:|
  Rat   379 QHQSTMELSEAGVEAAAATSTAMTRMSL----SSFFLNRPFIFFIMEETIGIPLFVGSVRNP 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	103/382 (27%)
Serpinf2	NP_001011892.1	alpha2AP	82..433	CDD:239008	103/382 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100