Protein Alignment Spn88Eb and Serpinb1b

DIOPT Version :10

• Sequence 1: NP_650427.1
• Gene: Spn88Eb / 41829
• FlyBaseID: FBgn0038299
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_766640.1
• Gene: Serpinb1b / 282663
• MGIID: 2445361
• Length: 382
• Species: Mus musculus
• Alignment Length: 395
• Identity: 107/395 - (27%)
• Similarity: 186/395 - (47%)
• Gaps: 37/395 - (9%)

  Fly    41 FSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGWALNKQQVLVSYTL 105
            |:|.|...::|..|:||:||||||..::|.:.:..:...|..:|::.|:.....:......|.|.
Mouse    11 FTLELFHTLKESSPTGNIFFSPFSISSSLAMVFLGAKGSTAAQLSKTLHFDSVEDIHSCFQSLTA 75

  Fly   106 AQRQDEFRWRQSPMELSSANRIFVDRTINVSNKF---NTLLYGA-TKELDFKNDPETGLKEINDW 166
                 |.....:...|..|||::.::|.|...:|   ...:|.| ...:||::..|...||||.|
Mouse    76 -----EVSKLGASHTLKLANRLYGEKTYNFLPEFLASTQKMYSADLAAVDFQHASEDARKEINQW 135

  Fly   167 IADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKPFFINEREQEMVYMMHK 231
            :..:|..:|.::|:...:...|.|||.||.|.||.|..||...||...||.:|:::.:.|.||::
Mouse   136 VKGQTEGKIPELLAKGVVDSMTKLVLVNAIYFKGIWEEQFMTRETINAPFRLNKKDTKTVKMMYQ 200

  Fly   232 TGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILP---NSNKISLNRVISRL 293
            ...|.......|:.:::::||:               ..::||:|:||   ......|.::..:|
Mouse   201 KKKFPFGYISDLKCKVLEMPYQ---------------GGELSMVILLPEDIEDESTGLKKIEEQL 250

  Fly   294 NADSVKKWFERALPQKIE--LSLPKFQFEQRLELTPILSLMGVNTMFTRNATFGDLT--ADPISL 354
            ....:.:|.:....:.|:  :.||:|:.|:...|...|..:||..:|:...  .||:  :....|
Mouse   251 TLGKLHEWTKHENLRNIDVHVKLPRFKMEESYILNSNLCCLGVQDLFSSGK--ADLSGMSGSRDL 313

  Fly   355 VIDDAQHLAKIKVDEVGSTAAAAT--ILLVSRSSRQPDPTK-FNCNHPFVFLIYDEKVDTILFAG 416
            .:....|.:.:.|:|.|:.|||||  |:.| ...:.|.|.: |..:|||:|.|.......::|.|
Mouse   314 FVSKIVHKSFVDVNEQGTEAAAATGGIIQV-LCEKMPTPQEVFTVDHPFLFFIRHNPTANMIFFG 377

  Fly   417 VYSDP 421
            ....|
Mouse   378 RVCSP 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	serpin_crustaceans_chelicerates_insects	34..421	CDD:381059	106/393 (27%)
Serpinb1b	NP_766640.1	serpinB1_LEI	1..382	CDD:381028	106/393 (27%)
		CARD-binding motif (CBM). /evidence=ECO:0000250|UniProtKB:P30740	352..382		8/29 (28%)