DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn88Eb and Serpina3b

DIOPT Version :9

Sequence 1:NP_650427.1 Gene:Spn88Eb / 41829 FlyBaseID:FBgn0038299 Length:426 Species:Drosophila melanogaster
Sequence 2:NP_766612.1 Gene:Serpina3b / 271047 MGIID:2182835 Length:420 Species:Mus musculus


Alignment Length:403 Identity:88/403 - (21%)
Similarity:176/403 - (43%) Gaps:56/403 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    20 LDKPELSFLNEFSQIFKGERDFSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTEREL 84
            ||...|:.:|         .||:.:..|::....|..|:.||||....||......:...|..|:
Mouse    42 LDSLTLASIN---------TDFAFSFYKELALKNPHKNIAFSPFGIATALNSLTLGAKGNTLEEI 97

  Fly    85 AQALNLGWALNKQQVL------VSYTLAQRQDEFRWRQSPMELSSANRIFVDRTINV----SNKF 139
            .:.|........:..:      :...|:...|:       :::.:.|.:||::.:.:    ..|.
Mouse    98 LEVLKFNLTETSEADIHQGFKHLLQRLSHPGDQ-------VQIRTGNALFVEKHLQILAEFKEKA 155

  Fly   140 NTLLYGATKELDFKNDPETGLKEINDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLS 204
            ..|.:......:|: .|...:|.||.:::::|..:|::::|  ::..:|.:|:.|..:.|.:|:.
Mouse   156 RALYHTEVFTANFQ-QPHEAMKLINSYMSNQTQGKIKELVS--DMDGNTSMVIVNDLFFKAEWMV 217

  Fly   205 QFKVEETALKPFFINEREQEMVYMMH----KTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHIST 265
            .|..::|.:..|.::......|.||.    :|..|:   ||.|:..:::|.|             
Mouse   218 PFNSDDTFMGKFIVDRSRHVKVPMMKTKNLRTPYFR---DEELKCTVVELNY------------- 266

  Fly   266 PESKSDISMIIILPNSNKISLNRVISRLNADSVKKWFERALPQKI-ELSLPKFQFEQRLELTPIL 329
               |.:...:.|||:..|  :.:|.:.|...::|||.:...|:|| ||.||||...|...|..||
Mouse   267 ---KGNGKAMFILPDQGK--MQQVEASLQPGTLKKWRKSLRPRKIKELHLPKFSLSQHYNLEDIL 326

  Fly   330 SLMGVNTMFTRNATFGDLTADPISLVIDDAQHLAKIKVDEVGSTAAAATILLVSRSSRQPDPTKF 394
            ..:|:..:|:..|....:|... ::.:.:..|..::.:.|.|:...|.||:..:..|.:..|...
Mouse   327 PELGIRELFSTQADLSGITGVK-NITVSEMIHSTELDMTEKGTEGDAITIVGYNFMSAKLKPVFV 390

  Fly   395 NCNHPFVFLIYDE 407
            .....|::::.|:
Mouse   391 KFEDQFLYIVLDQ 403

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn88EbNP_650427.1 SERPIN 37..418 CDD:238101 84/386 (22%)
Serpina3bNP_766612.1 SERPIN 51..414 CDD:294093 85/394 (22%)
RCL 367..392 6/24 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11461
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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