Protein Alignment Spn88Eb and SERPINA11

DIOPT Version :10

• Sequence 1: NP_650427.1
• Gene: Spn88Eb / 41829
• FlyBaseID: FBgn0038299
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_001073920.1
• Gene: SERPINA11 / 256394
• HGNCID: 19193
• Length: 422
• Species: Homo sapiens
• Alignment Length: 400
• Identity: 104/400 - (26%)
• Similarity: 183/400 - (45%)
• Gaps: 54/400 - (13%)

  Fly    40 DFSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGWALNKQQVL---- 100
            :|:|.|.|::....| ||:||||.|....|.|....:...|...:.:.|........:..:
Human    56 NFALRLYKELAADAP-GNIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIHQGF 119

  Fly   101 --VSYTLAQRQDEFRWRQSP-MELSSANRIFVDRTINVSNKF-NTL--LYGA-TKELDFKNDPET 158
              :.:|||        ..|| :||...|.:|:|:.:.....: :::  |||| ....:|.:...|
Human   120 RSLLHTLA--------LPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTT 176

  Fly   159 GLKEINDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEET-ALKPFFINERE 222
            | ::|||::..:|:.|:.|.|  .|.:..|.:||||..:.|.:|...|...:| ..:.||::||.
Human   177 G-RQINDYLRRQTYGQVVDCL--PEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERT 238

  Fly   223 QEMVYMMHKTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPNSNKISLN 287
            ...|.|||:....:...|:.|...::::.||                .:...:::||:..|  :.
Human   239 SLQVPMMHQKEMHRFLYDQDLACTVLQIEYR----------------GNALALLVLPDPGK--MK 285

  Fly   288 RVISRLNADSVKKWFERALPQKIELSLPKFQFEQRLELTPILSLMGVNTMFTRNATFGDLTADPI 352
            :|.:.|...:::||.:..||..::|.||:|.......|..||..:|:..:....|.|..:|.. :
Human   286 QVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQ-L 349

  Fly   353 SLVIDDAQHLAKIKVDEVGSTAAAATILLVSRSSRQP------DPTKFNCNHPFVFLIYDEKVDT 411
            :..|....|.|.:.:.|.|:.|.||:.||    |:.|      || ..:.|.||:.|:::....:
Human   350 NKTISKVSHKAMVDMSEKGTEAGAASGLL----SQPPSLNTMSDP-HAHFNRPFLLLLWEVTTQS 409

  Fly   412 ILFAGVYSDP 421
            :||.|...:|
Human   410 LLFLGKVVNP 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	serpin_crustaceans_chelicerates_insects	34..421	CDD:381059	103/398 (26%)
SERPINA11	NP_001073920.1	serpinA11	50..422	CDD:381025	103/399 (26%)