Protein Alignment Spn88Eb and Serpina1

DIOPT Version :9

• Sequence 1: NP_650427.1
• Gene: Spn88Eb / 41829
• FlyBaseID: FBgn0038299
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_071964.2
• Gene: Serpina1 / 24648
• RGDID: 3326
• Length: 411
• Species: Rattus norvegicus
• Alignment Length: 402
• Identity: 98/402 - (24%)
• Similarity: 174/402 - (43%)
• Gaps: 44/402 - (10%)

  Fly    31 FSQIFKGERDFSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGWA-- 93
            :.:|.....||:.:|.:::.....:.|:||||.|...|..:....|...|.:::.:.|.....
  Rat    41 YRKISSNLADFAFSLYRELVHQSNTSNIFFSPMSITTAFAMLSLGSKGDTRKQILEGLEFNLTQI 105

  Fly    94 ----LNKQQVLVSYTLAQRQDEFRWRQSPMELSSANRIFVDRTINVSNKF----NTLLYGATKEL 150
                ::|....:..|| .|.|      |.::|::.|.:||::.:.:..||    ....:.....:
  Rat   106 PEADIHKAFHHLLQTL-NRPD------SELQLNTGNGLFVNKNLKLVEKFLEEVKNNYHSEAFSV 163

  Fly   151 DFKNDPETGLKEINDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKP 215
            :|. |.|...|.|||::...|..:|.|::  :::...|:..|.|..:.||:|...|..|.|....
  Rat   164 NFA-DSEEAKKVINDYVEKGTQGKIVDLM--KQLDEDTVFALVNYIFFKGKWKRPFNPEHTRDAD 225

  Fly   216 FFINEREQEMVYMMHKTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPN 280
            |.:::.....|.||::.|.|.|.....|.|.::.:.|                ..:.:.|.:||:
  Rat   226 FHVDKSTTVKVPMMNRLGMFDMHYCSTLSSWVLMMDY----------------LGNATAIFLLPD 274

  Fly   281 SNKISLNRVISRLNADSVKKWFERALPQKIELSLPKFQFEQRLELTPILSLMGVNTMFTRNATFG 345
            ..|  :..:...|..|.:.::......:...|..||........|..:||.:|:..:|..:|...
  Rat   275 DGK--MQHLEQTLTKDLISRFLLNRQTRSAILYFPKLSISGTYNLKTLLSSLGITRVFNNDADLS 337

  Fly   346 DLTAD-PISLVIDDAQHLAKIKVDEVGSTAAAATILLVSRSSRQPDPTKFNCNHPFVFLIYDEKV 409
            .:|.| |:.|  ..|.|.|.:.:||.|:.||.||::.....|..|. .||  :|||:|:|.:.:.
  Rat   338 GITEDAPLKL--SQAVHKAVLTLDERGTEAAGATVVEAVPMSLPPQ-VKF--DHPFIFMIVESET 397

  Fly   410 DTILFAGVYSDP 421
            .:.||.|...||
  Rat   398 QSPLFVGKVIDP 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	95/391 (24%)
Serpina1	NP_071964.2	alpha-1-antitrypsin_like	49..406	CDD:239011	95/389 (24%)
		RCL	367..386		6/21 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100