DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn88Eb and Serpinb9

DIOPT Version :9

Sequence 1:	NP_650427.1	Gene:	Spn88Eb / 41829	FlyBaseID:	FBgn0038299	Length:	426	Species:	Drosophila melanogaster
Sequence 2:	NP_033282.1	Gene:	Serpinb9 / 20723	MGIID:	106603	Length:	374	Species:	Mus musculus

Alignment Length:	403	Identity:	110/403 - (27%)
Similarity:	202/403 - (50%)	Gaps:	38/403 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 LNEFSQIFKGERDFSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGW 92
            :|..|:   |...|::.|:|.:.:..||.|:.:||.|..:||.:....:..||..:::|||
Mouse     1 MNTLSE---GNGTFAIHLLKMLCQSNPSKNVCYSPASISSALAMVLLGAKGQTAVQISQAL---- 58

  Fly    93 ALNKQQ-VLVSYTLAQRQDEFRWRQSPMELSSANRIFVDRTINVSNKF--NTLLY--GATKELDF 152
            .|||:: :...:.|..|  :.........|..|||:|.|:|..|...|  ::|.:  ...::|.|
Mouse    59 GLNKEEGIHQGFQLLLR--KLNKPDRKYSLRVANRLFADKTCEVLQTFKESSLHFYDSEMEQLSF 121

  Fly   153 KNDPETGLKEINDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKPFF 217
            ..:.|...:.||.|::.:|..:|.::||...:...|.|||.||.|.||:|...|..|.|...||.
Mouse   122 AEEAEVSRQHINTWVSKQTEGKIPELLSGGSVDSETRLVLINALYFKGKWHQPFNKEYTMDMPFK 186

  Fly   218 INEREQEMVYMMHKTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPNSN 282
            ||:.|:..|.||.:...:.:...:.:|:|::.:||..:               ::|::::||:..
Mouse   187 INKDEKRPVQMMCREDTYNLAYVKEVQAQVLVMPYEGM---------------ELSLVVLLPDEG 236

  Fly   283 KISLNRVISRLNADSVKKWFERALPQK--IELSLPKFQFEQRLELTPILSLMGVNTMFTRNATFG 345
             :.|::|.:.|..:.:..|.|....:.  :|:.||||:.::..::..:...:||..:|..:.  .
Mouse   237 -VDLSKVENNLTFEKLTAWMEADFMKSTDVEVFLPKFKLQEDYDMESLFQRLGVVDVFQEDK--A 298

  Fly   346 DLT--ADPISLVIDDAQHLAKIKVDEVGSTAAAATILLVSRSSRQPDPTKFNCNHPFVFLIYDEK 408
            ||:  :...:|.:....|.:.::::|.|:.||||: .::........|| |..:|||:|.|...|
Mouse   299 DLSGMSPERNLCVSKFVHQSVVEINEEGTEAAAAS-AIIEFCCASSVPT-FCADHPFLFFIRHNK 361

  Fly   409 VDTILFAGVYSDP 421
            .::|||.|.:|.|
Mouse   362 ANSILFCGRFSSP 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	106/389 (27%)
Serpinb9	NP_033282.1	serpin	1..374	CDD:393296	109/401 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920