DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn88Eb and Serpinb6b

DIOPT Version :9

Sequence 1:	NP_650427.1	Gene:	Spn88Eb / 41829	FlyBaseID:	FBgn0038299	Length:	426	Species:	Drosophila melanogaster
Sequence 2:	NP_035584.1	Gene:	Serpinb6b / 20708	MGIID:	894688	Length:	377	Species:	Mus musculus

Alignment Length:	395	Identity:	119/395 - (30%)
Similarity:	191/395 - (48%)	Gaps:	28/395 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 IFKGERDFSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGWALNKQQ 98
            :.:....|:|.|:|.:.| ..|.|:.|||.|..:||.:.:..:...|..::||||:|.....|..
Mouse     4 LLEANATFALNLLKTLGE-DSSRNVLFSPISVSSALAMVFMGAKGTTASQMAQALSLDKCSGKGG 67

  Fly    99 VLVSYTLAQRQDEFRWRQSPMELSSANRIFVDRTINVSNKFN---TLLYGA-TKELDFKNDPETG 159
            ..|.........|.....:...|.:|||:|.::|.::...|.   ...|.| .:|||||...|..
Mouse    68 RDVHQGFQSLLTETNKTGTQYVLRTANRLFGEKTFDILASFKDSCRKFYEAEMEELDFKGATEQS 132

  Fly   160 LKEINDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKPFFINEREQE 224
            .:.||.|:|.||.::|.::|||..:..:|.|||.||.|.||.|..||..|:|...||.:.:...:
Mouse   133 RQHINAWVAKKTEDKITELLSSGSVNSNTPLVLVNAIYFKGNWEKQFNKEDTQEMPFNVTKDVVK 197

  Fly   225 MVYMMHKTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPNSNKISLNRV 289
            .|.||.:...||||..|.:.:.|:.|||               ..::::|||:||:.: |.|:.|
Mouse   198 PVQMMFQKSTFKMTYVEEISTNILLLPY---------------VGNELNMIIMLPDEH-IELSMV 246

  Fly   290 ISRLNADSVKKW--FERALPQKIELSLPKFQFEQRLELTPILSLMGVNTMFTRN-ATFGDLTADP 351
            ...:......:|  .::...:::|:.||||:.|:..::..:|..:|:...|... |.|..: |..
Mouse   247 EKEITYKKFIEWTRLDKMEEEEVEVFLPKFKLEENYDMKDVLCRLGMTDAFEEGMADFSGI-ASK 310

  Fly   352 ISLVIDDAQHLAKIKVDEVGSTAAAATILLVSRSSRQPDPTKFNCNHPFVFLIYDEKVDTILFAG 416
            ..|.:....|.:.::|:|.|:.|||||...:......|   .|..||||:|.|...:...|:|.|
Mouse   311 EGLFLSKVIHKSFVEVNEEGTEAAAATAANIGFRCMVP---YFCANHPFLFFIQHSRTSGIVFCG 372

  Fly   417 VYSDP 421
            .:|.|
Mouse   373 RFSSP 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	117/387 (30%)
Serpinb6b	NP_035584.1	serpin	1..377	CDD:393296	118/393 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820