Protein Alignment Spn88Eb and Serpina1b

DIOPT Version :10

• Sequence 1: NP_650427.1
• Gene: Spn88Eb / 41829
• FlyBaseID: FBgn0038299
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_033270.3
• Gene: Serpina1b / 20701
• MGIID: 891970
• Length: 413
• Species: Mus musculus
• Alignment Length: 400
• Identity: 93/400 - (23%)
• Similarity: 167/400 - (41%)
• Gaps: 57/400 - (14%)

  Fly    40 DFSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGWA------LNKQQ 98
            ||:::|.:::.....:.|:||||.|...|..:....|...|..::.:.|.....      ::|..
Mouse    50 DFAISLYRELVHQSNTSNIFFSPVSIATAFAMLSLGSKGDTHTQILEGLQFNLTQTSEADIHKSF 114

  Fly    99 VLVSYTLAQRQDEFRWRQSPMELSSANRIFVDRTINVSNKFNTLLYGATKELDFKN--------- 154
            ..:..|| .|.|      |.::||:.|.:||:..:.:..||..         :.||
Mouse   115 QHLLQTL-NRPD------SELQLSTGNGLFVNNDLKLVEKFLE---------EAKNHYQAEVFSV 163

  Fly   155 ---DPETGLKEINDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKPF 216
               :.|...|.|||::...|..:|.:.:  :|:...|:..|||....||:|...|..|.|....|
Mouse   164 NFAESEEAKKVINDFVEKGTQGKIVEAV--KELDQDTVFALANYILFKGKWKKPFDPENTEEAEF 226

  Fly   217 FINEREQEMVYMMHKTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPNS 281
            .:::.....|.||..:|...:.....|.|.::.:.|                ..:.|.:.:||..
Mouse   227 HVDKSTTVKVPMMMLSGMLDVHHCSILSSWVLLMDY----------------AGNASAVFLLPED 275

  Fly   282 NKISLNRVISRLNADSVKKWFERALPQKIELSLPKFQFEQRLELTPILSLMGVNTMFTRNATFGD 346
            .|  :..:...||.:.:.|.......:.:::.:|:........|..::|.:|:..:|...|....
Mouse   276 GK--MQHLEQTLNKELISKILLNRRRRLVQIHIPRLSISGDYNLKTLMSPLGITRIFNNGADLSG 338

  Fly   347 LTADPISLVIDDAQHLAKIKVDEVGSTAAAATILLVSRSSRQPDPTKFNCNHPFVFLIYDEKVDT 411
            :|.:...|.:..|.|.|.:.:||.|:.|||||:......| .|...:|  :|||:|:|::|...:
Mouse   339 ITEENAPLKLSKAVHKAVLTIDETGTEAAAATVFEAVPMS-MPPILRF--DHPFLFIIFEEHTQS 400

  Fly   412 ILFAGVYSDP 421
            .:|.|...||
Mouse   401 PIFVGKVVDP 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	serpin_crustaceans_chelicerates_insects	34..421	CDD:381059	91/398 (23%)
Serpina1b	NP_033270.3	serpinA1_A1AT	44..412	CDD:381012	92/399 (23%)
		RCL	368..387		6/21 (29%)