DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn88Eb and Serpina1b

DIOPT Version :9

Sequence 1:NP_650427.1 Gene:Spn88Eb / 41829 FlyBaseID:FBgn0038299 Length:426 Species:Drosophila melanogaster
Sequence 2:NP_033270.3 Gene:Serpina1b / 20701 MGIID:891970 Length:413 Species:Mus musculus


Alignment Length:400 Identity:93/400 - (23%)
Similarity:167/400 - (41%) Gaps:57/400 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    40 DFSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGWA------LNKQQ 98
            ||:::|.:::.....:.|:||||.|...|..:....|...|..::.:.|.....      ::|..
Mouse    50 DFAISLYRELVHQSNTSNIFFSPVSIATAFAMLSLGSKGDTHTQILEGLQFNLTQTSEADIHKSF 114

  Fly    99 VLVSYTLAQRQDEFRWRQSPMELSSANRIFVDRTINVSNKFNTLLYGATKELDFKN--------- 154
            ..:..|| .|.|      |.::||:.|.:||:..:.:..||..         :.||         
Mouse   115 QHLLQTL-NRPD------SELQLSTGNGLFVNNDLKLVEKFLE---------EAKNHYQAEVFSV 163

  Fly   155 ---DPETGLKEINDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKPF 216
               :.|...|.|||::...|..:|.:.:  :|:...|:..|||....||:|...|..|.|....|
Mouse   164 NFAESEEAKKVINDFVEKGTQGKIVEAV--KELDQDTVFALANYILFKGKWKKPFDPENTEEAEF 226

  Fly   217 FINEREQEMVYMMHKTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPNS 281
            .:::.....|.||..:|...:.....|.|.::.:.|                ..:.|.:.:||..
Mouse   227 HVDKSTTVKVPMMMLSGMLDVHHCSILSSWVLLMDY----------------AGNASAVFLLPED 275

  Fly   282 NKISLNRVISRLNADSVKKWFERALPQKIELSLPKFQFEQRLELTPILSLMGVNTMFTRNATFGD 346
            .|  :..:...||.:.:.|.......:.:::.:|:........|..::|.:|:..:|...|....
Mouse   276 GK--MQHLEQTLNKELISKILLNRRRRLVQIHIPRLSISGDYNLKTLMSPLGITRIFNNGADLSG 338

  Fly   347 LTADPISLVIDDAQHLAKIKVDEVGSTAAAATILLVSRSSRQPDPTKFNCNHPFVFLIYDEKVDT 411
            :|.:...|.:..|.|.|.:.:||.|:.|||||:......| .|...:|  :|||:|:|::|...:
Mouse   339 ITEENAPLKLSKAVHKAVLTIDETGTEAAAATVFEAVPMS-MPPILRF--DHPFLFIIFEEHTQS 400

  Fly   412 ILFAGVYSDP 421
            .:|.|...||
Mouse   401 PIFVGKVVDP 410

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn88EbNP_650427.1 SERPIN 37..418 CDD:238101 91/395 (23%)
Serpina1bNP_033270.3 SERPIN 53..410 CDD:214513 89/395 (23%)
RCL 368..387 6/21 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11461
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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