DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn88Eb and Serpinb3a

DIOPT Version :10

Sequence 1:NP_650427.1 Gene:Spn88Eb / 41829 FlyBaseID:FBgn0038299 Length:426 Species:Drosophila melanogaster
Sequence 2:NP_033152.3 Gene:Serpinb3a / 20248 MGIID:3573933 Length:387 Species:Mus musculus


Alignment Length:407 Identity:112/407 - (27%)
Similarity:200/407 - (49%) Gaps:56/407 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    41 FSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGWALNKQQVLVSYTL 105
            |:|.|.:|:||  ...|:|:||.|...||.:....:...||:::.:.|.......|.....::..
Mouse    11 FTLELYRQLRE--SDNNIFYSPISMMTALAMLQLGAKGNTEKQIEKVLQFNETTKKTTEKSAHCH 73

  Fly   106 AQRQDEFRWRQSPMELSSANRIFVDRTINVSNKFNTLLYGA--------------------TKEL 150
            .:.....::::...:|:.:|..:   .:..:|.    :|||                    .:.|
Mouse    74 DEENVHEQFQKLMTQLNKSNDAY---DLKAANS----IYGAKGFPFVQTFLEDIKEYYQANVESL 131

  Fly   151 DFKNDPETGLKEINDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKP 215
            ||::..|...|:||.|:..:|:.:|:|:..:..:...|::||.||.|.||||..:|..:.|..:.
Mouse   132 DFEHAAEESEKKINSWVESQTNGKIKDLFPNGSLNRSTIMVLVNAVYFKGQWNHKFDEKHTTEEK 196

  Fly   216 FFINEREQEMVYMMHKTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPN 280
            |::|:...:.|.||.:...|.....|.:|::|:::|    ||.||           :|||::|| 
Mouse   197 FWLNKNTSKPVQMMKQNIEFNFMFLEDVQAKIVEIP----YKGKE-----------LSMIVLLP- 245

  Fly   281 SNKISLN---RVISRLNADSVKKW--FERALPQKIELSLPKFQFEQRLELTPILSLMG-VNTMFT 339
               :.:|   ::..:|.||.:.:|  .|.....::.||||:|:.:::.:|...|..|| |:....
Mouse   246 ---VEINGLKQLEEQLTADKLLEWTRAENMHMTELYLSLPRFKVDEKYDLPIPLEHMGMVDAFDP 307

  Fly   340 RNATFGDLTADPISLVIDDAQHLAKIKVDEVGSTAAAATILLVSRSSRQPDPTKFNCNHPFVFLI 404
            :.|.|..:::.. .||:....|.:.::|:|.|:.|||||.:.||.:|.| ....|.|:|||:|.|
Mouse   308 QKADFSGMSSTQ-GLVVSKVLHKSFVEVNEEGTEAAAATGVEVSLTSAQ-IAEDFCCDHPFLFFI 370

  Fly   405 YDEKVDTILFAGVYSDP 421
            ...|.::|||.|..|.|
Mouse   371 IHRKTNSILFFGRISSP 387

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn88EbNP_650427.1 serpin_crustaceans_chelicerates_insects 34..421 CDD:381059 111/405 (27%)
Serpinb3aNP_033152.3 serpin 1..387 CDD:476815 111/405 (27%)

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