DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn88Eb and Serpina16

DIOPT Version :10

Sequence 1:NP_650427.1 Gene:Spn88Eb / 41829 FlyBaseID:FBgn0038299 Length:426 Species:Drosophila melanogaster
Sequence 2:XP_112098.3 Gene:Serpina16 / 194604 MGIID:2684892 Length:440 Species:Mus musculus


Alignment Length:449 Identity:110/449 - (24%)
Similarity:177/449 - (39%) Gaps:71/449 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 SLVLLALLPVVTIAALDKP-----ELSFLNEFSQI-----FKGERDFSLALMKQIREIYPSGNLF 59
            |::.|.||..|.:.....|     |.|..:....|     |...:.|:|:|..|:.:.....|:.
Mouse    26 SILSLWLLLAVLVPCFGGPVTPPTETSNTSRTPAIQGAPPFFNNQKFALSLYTQLPKSKLGKNVI 90

  Fly    60 FSPFSTYNALLLAYFSSSEQTERELAQALNLG--WALNKQQV-----LVSYTLAQRQDEFRWRQS 117
            |||.|....|:|..|....:..|::.|.|..|  .||:.:..     |:|..|            
Mouse    91 FSPLSITMPLVLLAFQDKPEARRQVLQGLGFGVTGALDAKAAVQYGKLLSALL------------ 143

  Fly   118 PME---LSSANRIFVDRTINVSNKFNTLLYGATKE----LDFKNDPETGLKEINDWIADKTHNQI 175
            |.|   :.:.:..|:|:|:.....|.||...:...    :.|.|. :...|:|:..|..||..::
Mouse   144 PAEHCGIHTGSLFFIDKTLKPQTTFLTLANSSYSSDVILISFGNH-KLAKKQIDLAIKVKTQGKV 207

  Fly   176 RDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKPFFINEREQEMVYMMHKTGAFKMTID 240
            ..:|  ..:.|.|.|.|.|....||:|..:|..:.|.::.|.::.....:|.||.|.|.|::...
Mouse   208 TRLL--RNLKPPTHLFLTNYNLFKGKWKYRFNPKYTGMRNFSLSNGTNILVPMMQKIGWFQLKYF 270

  Fly   241 EGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPNSNKISLNRVISRLNADSVKKWFERA 305
            ..:.|.:::||:                ..:||.:..|||..  .|......|...|...|.:..
Mouse   271 SHIHSYVLQLPF----------------TCNISGVFFLPNDG--DLKECEKALLEQSFNTWIQPF 317

  Fly   306 LPQKIELSLPKFQFEQRLELTPILSLMGVNT---MFTRNATFGDLTADPISLVIDDAQHLAKIKV 367
            ..:|..|..|||.....|:|.   |...||:   :|.:......:|.....|.:..|.|.|::.|
Mouse   318 PLRKRWLFFPKFSIPVALQLE---SFKHVNSSLKLFNKRMDLSGITLQKAPLRVTMAVHRAELAV 379

  Fly   368 DEVGSTAAAATILLVSRSSRQPDP--TKFNCNHPFVFLIYDEKVDTILFAGVYSDPRQM 424
            .|.|....      ||.|...|:|  ...:.|..|:.||.||...::||.|...:|.::
Mouse   380 SEDGEGED------VSNSRVNPEPGLAALHFNRSFLLLILDEASKSLLFMGRVLNPTRV 432

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn88EbNP_650427.1 serpin_crustaceans_chelicerates_insects 34..421 CDD:381059 101/410 (25%)
Serpina16XP_112098.3 serpin 61..431 CDD:476815 101/411 (25%)

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