Protein Alignment Spn88Eb and Serpina12

DIOPT Version :9

• Sequence 1: NP_650427.1
• Gene: Spn88Eb / 41829
• FlyBaseID: FBgn0038299
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_620180.2
• Gene: Serpina12 / 191570
• RGDID: 708485
• Length: 414
• Species: Rattus norvegicus
• Alignment Length: 438
• Identity: 111/438 - (25%)
• Similarity: 206/438 - (47%)
• Gaps: 52/438 - (11%)

  Fly     5 SLVL---LALLPVVTIAAL----DKPELSFLNEFSQIFKGERD----------FSLALMKQIREI 52
            :|||   |.|..::|:..|    |.|:........|.::|::|          |...|::::...
  Rat     2 NLVLGLGLFLAGLLTVKGLLQDRDAPDTYESPVRVQEWRGKKDARELTRHNMEFGFKLLQRLASN 66

  Fly    53 YPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGWALNKQQVLVSYTLAQRQDEFRWRQS 117
            ...||:|.||.|...|..:....:...|..|:.:..|.....::...:..:.|.|:.:.   ...
  Rat    67 SRQGNIFLSPLSISTAFSMLSLGAQNSTLEEIREGFNFKEMSDRDMHMGFHYLLQKLNR---ETQ 128

  Fly   118 PMELSSANRIFVDRTINVSNKFNTL---LYGATKELDFKNDPETGLKEINDWIADKTHNQIRDML 179
            .:::|..|.:|:|:.:....:|..|   ||.|...|....|.|...|.||.:|:.||||:|.:|:
  Rat   129 DVKMSIGNALFMDQRLRPQQRFLKLAKNLYDADMILTNFQDLENTQKNINKYISRKTHNRIENMV 193

  Fly   180 SSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKPFFINEREQEMVYMMHKTGAFKMTIDEGLQ 244
              :.|.|.|:::|.|..|.:|:|..:|..::|..:.|||.|.:...|.||.:.|.:.|..|..|.
  Rat   194 --KNIDPGTVMLLTNYIYFQGRWQYEFDPKQTKEEDFFIEEGKTVKVPMMFQRGMYDMAYDSQLS 256

  Fly   245 SQIIKLPYRTIYKSKETHISTPESKSDISMIIILPNSNKISLNRVISRLNADSVKKWFERALPQK 309
            ..|:::|||                .:|:...:||:|.|:.|  :...|.||...||......:.
  Rat   257 CTILEMPYR----------------RNITATFVLPDSGKLRL--LEQGLQADIFAKWKSLLSKRV 303

  Fly   310 IELSLPKFQFEQRLELTPILSLMGVNTMFTRNATFGDLT--ADPISLVIDDAQHLAKIKVDEVGS 372
            :::.:|:........:..:||.:|::.:|..:   ||||  :...||.:.:|.|.|:::::|.|:
  Rat   304 VDVWVPRLHISATYNMKKVLSRLGISKIFEEH---GDLTRISSHRSLKVGEAVHKAELRMNEKGT 365

  Fly   373 TAAAATILLVSRSSRQPDPTKFNCNHPFVFLIYDEKVDTILF-AGVYS 419
            ..||.:   .:::.....|.:...|.||:.:||:..:.:::| |.:|:
  Rat   366 EGAAGS---GAQTLPMETPRRMKLNAPFLMMIYENLMPSMIFLARIYN 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	100/396 (25%)
Serpina12	NP_620180.2	alpha-1-antitrypsin_like	51..408	CDD:239011	98/385 (25%)
		Reactive center loop. /evidence=ECO:0000250|UniProtKB:Q8IW75	364..382		3/20 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010