DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn88Eb and Serpinf2

DIOPT Version :9

Sequence 1:	NP_650427.1	Gene:	Spn88Eb / 41829	FlyBaseID:	FBgn0038299	Length:	426	Species:	Drosophila melanogaster
Sequence 2:	NP_032904.1	Gene:	Serpinf2 / 18816	MGIID:	107173	Length:	491	Species:	Mus musculus

Alignment Length:	385	Identity:	97/385 - (25%)
Similarity:	167/385 - (43%)	Gaps:	41/385 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 FSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGWALNKQQVLVSYTL 105
            |:..|...:.:...|.||..||.|...||......:..||...|.:.|::.         ....|
Mouse    89 FTTDLFSLVAQTSTSSNLVLSPLSVALALSHLALGAQNQTLHSLHRVLHMN---------TGSCL 144

  Fly   106 AQRQDEFRWRQSPMELSSANRIFVDRTINVSNKF---NTLLYGATKELDFKNDPETGLKEINDWI 167
            ......|.....|..:..|.||::.:...:.:.|   :..|:|| |.:......|..|..||.|:
Mouse   145 PHLLSHFYQNLGPGTIRLAARIYLQKGFPIKDDFLEQSERLFGA-KPVKLTGKQEEDLANINQWV 208

  Fly   168 ADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKPFFINEREQEMVYMMHKT 232
            .:.|..:|.|.||  |:...|:|:|.||.:..|.|.::|....|....|.::||....|.|||..
Mouse   209 KEATEGKIEDFLS--ELPDSTVLLLLNAIHFHGFWRTKFDPSLTQKDFFHLDERFTVSVDMMHAV 271

  Fly   233 G-AFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPNSNKISLNRVISRLNAD 296
            . ..:..:.|..:.|:...|:                |:::|.::::|...:.:::.|::.|..|
Mouse   272 SYPLRWFLLEQPEIQVAHFPF----------------KNNMSFVVVMPTYFEWNVSEVLANLTWD 320

  Fly   297 SVKKWFERALPQKIELSLPKFQFEQRLELTPILSLMGVNTMFTRNATFGDLTADPISLVIDDAQH 361
            ::.....:..|.|:  .|||...:|:|:|...||.:|:..:|......|   ....:||:...||
Mouse   321 TLYHPSLQERPTKV--WLPKLHLQQQLDLVATLSQLGLQELFQGPDLRG---ISEQNLVVSSVQH 380

  Fly   362 LAKIKVDEVGSTAAAATILLVSRSSRQPDPTKFNCNHPFVFLIYDEKVDTILFAGVYSDP 421
            .:.:::.|.|..|||||.:.::|.|.    :.|..|.||:|.|.::.:...||.|...:|
Mouse   381 QSTMELSEAGVEAAAATSVAMNRMSL----SSFTVNRPFLFFIMEDTIGVPLFVGSVRNP 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	96/380 (25%)
Serpinf2	NP_032904.1	alpha2AP	82..433	CDD:239008	96/380 (25%)
Serpinf2	NP_032904.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	439..491
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100