Protein Alignment Spn88Eb and Serpine1

DIOPT Version :10

• Sequence 1: NP_650427.1
• Gene: Spn88Eb / 41829
• FlyBaseID: FBgn0038299
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_032897.2
• Gene: Serpine1 / 18787
• MGIID: 97608
• Length: 402
• Species: Mus musculus
• Alignment Length: 393
• Identity: 105/393 - (26%)
• Similarity: 189/393 - (48%)
• Gaps: 38/393 - (9%)

  Fly    40 DFSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGWALNKQQVLVSYT 104
            ||.:.:.:|:.:.....|:.|||:...:.|.:...:::.:|.|::..|  :|:.:|::.  .::.
Mouse    37 DFGVKVFQQVVQASKDRNVVFSPYGVSSVLAMLQMTTAGKTRRQIQDA--MGFKVNEKG--TAHA 97

  Fly   105 LAQRQDEFRWRQSPMELSSANRIFVDRTINVSN----KFNTLLYGATKELDFKNDPETGLKEIND 165
            |.|...|.....:..|:|:|:.|||.|.:.:..    .|..|.....|::|| ::.|.....|||
Mouse    98 LRQLSKELMGPWNKNEISTADAIFVQRDLELVQGFMPHFFKLFQTMVKQVDF-SEVERARFIIND 161

  Fly   166 WIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKPFFINEREQEMVYMMH 230
            |:...|...|.|:|:...:...|.|||.||.|..|||.:.|....|..:.|..::.....|.||.
Mouse   162 WVERHTKGMISDLLAKGAVDELTRLVLVNALYFSGQWKTPFLEASTHQRLFHKSDGSTVSVPMMA 226

  Fly   231 KTGAF---KMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPNSNKISLNRVISR 292
            ::..|   :.|..:||:..:::|||:               ...:||.|..|....:.|:.:.:.
Mouse   227 QSNKFNYTEFTTPDGLEYDVVELPYQ---------------GDTLSMFIAAPFEKDVHLSALTNI 276

  Fly   293 LNADSVKKWFER--ALPQKIELSLPKFQFEQRLELTPILSLMGVNTMFTRNATFGDLT--ADPIS 353
            |:|:.:::|...  .||:.  |.||||..|..::|...|..:|:..||  :||..|.|  :|...
Mouse   277 LDAELIRQWKGNMTRLPRL--LILPKFSLETEVDLRGPLEKLGMPDMF--SATLADFTSLSDQEQ 337

  Fly   354 LVIDDAQHLAKIKVDEVGSTAAAATILLVSRSSRQPDPTKFNCNHPFVFLIYDEKVDTILFAGVY 418
            |.:..|....:|:|:|.|:.|:::|..::   |.:..||:...:..|:|::.....:||||.|..
Mouse   338 LSVAQALQKVRIEVNESGTVASSSTAFVI---SARMAPTEMVIDRSFLFVVRHNPTETILFMGQV 399

  Fly   419 SDP 421
            .:|
Mouse   400 MEP 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	serpin_crustaceans_chelicerates_insects	34..421	CDD:381059	104/391 (27%)
Serpine1	NP_032897.2	serpin	29..402	CDD:476815	104/391 (27%)