DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn88Eb and Serpinb7

DIOPT Version :9

Sequence 1:	NP_650427.1	Gene:	Spn88Eb / 41829	FlyBaseID:	FBgn0038299	Length:	426	Species:	Drosophila melanogaster
Sequence 2:	NP_081824.1	Gene:	Serpinb7 / 116872	MGIID:	2151053	Length:	380	Species:	Mus musculus

Alignment Length:	399	Identity:	111/399 - (27%)
Similarity:	183/399 - (45%)	Gaps:	45/399 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 DFSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNL------GWALNKQQ 98
            :|...|.:::.....:||:|||..|.:.||.|....:.....|::.:||:.      |.:.|.|.
Mouse    10 EFGFDLFREMDSSQGNGNVFFSSLSIFTALTLIRLGARGDCARQIDKALHFNIPSRQGNSSNNQP 74

  Fly    99 VLVSYTLAQRQDEFRWRQSPMELSSANRIFVDRTINVSNKFNTL---LYGATKE-LDFKNDPETG 159
            .| .|.|.:...:........|||.|..:|.::..:....:...   ||.|..| :||.||.:..
Mouse    75 GL-QYQLKRVLADINSSHKDYELSIATGVFAEKVYDFHKNYIECAENLYNAKVERVDFTNDVQDT 138

  Fly   160 LKEINDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKPFFINEREQE 224
            ..:||.||.::||.:|:.:|....::...::||.||.|.||:|.|.|...:|....|.......:
Mouse   139 RFKINKWIENETHGKIKKVLGDSSLSSSAVMVLVNAVYFKGKWKSAFTKTDTLSCRFRSPTCPGK 203

  Fly   225 MVYMMHKTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPNSNKISLNRV 289
            :|.|||:...|.::..:....|:::|.|.                ..|||.|:||..   .|..:
Mouse   204 VVNMMHQERRFNLSTIQQPPMQVLELQYH----------------GGISMYIMLPED---GLCEI 249

  Fly   290 ISRLNADSVKKWFER--ALPQKIELSLPKFQFEQRLELTPILSLMGVNTMFTRNATFGDLT--AD 350
            .|:|:..::..|..|  ...|.:.:.||:|:.|:..|:|..|..:|:..:|..::  .||:  |.
Mouse   250 ESKLSFQNLMDWTNRRKMKSQYVNVFLPQFKIEKNYEMTHHLKSLGLKDIFDESS--ADLSGIAS 312

  Fly   351 PISLVIDDAQHLAKIKVDEVGSTAAAAT---ILLVSRSSRQPDPTKFNCNHPFVFLIYDEKVDTI 412
            ...|.:....|.:.|:|.|.|:.|.|||   |:    ..:.|:.|.|..:.||:|:|  :|.|.|
Mouse   313 GGRLYVSKLMHKSFIEVSEEGTEATAATENNIV----EKQLPESTVFRADRPFLFVI--KKNDII 371

  Fly   413 LFAGVYSDP 421
            ||.|..|.|
Mouse   372 LFTGKVSCP 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	109/394 (28%)
Serpinb7	NP_081824.1	SERPIN	4..380	CDD:294093	110/397 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920